WOS

Permanent URI for this collectionhttps://hdl.handle.net/11443/932

Browse

Has files: NoSubject: search.filters.subject.Carcinoma

Search Results

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Cytoreductive Surgery Followed by Hyperthermic Intraperitoneal Chemotherapy: Morbidity and Mortality Analysis of Our Patients
    (ORTADOGU AD PRES \& PUBL CO, 2012-01-01) Karadayi, Kursat; Turan, Mustafa; Karadayi, Sule; Alagozlu, Hakan; Kilickap, Saadettin; Buyukcelik, Abdullah; Sarkis, Cihat; Yucel, Birsen; Boztosun, Abdullah; Cetin, Meral; Yilmaz, Abdulkerim; Yanik, Ali; Sen, Metin
    Objective: The purpose of this study was to analyze the morbidity and mortality of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) and early postoperative intraperitoneal chemotherapy (EPIC) with closed abdomen technique in the treatment of peritoneal surface malignancies. Material and Methods: Twenty-six patients (8 with ovarian cancer, 7 peritoneal mesothelioma, 6 colorectal cancer, 3 uterine sarcoma, 1 peritoneal carcinoma and 1 with gastric cancer) underwent 27 procedures. Peritonectomy was performed with complete removal of all the involved visceral and parietal peritoneum. HIPEC was performed with the closed abdominal technique using preheated (42.5 degrees C) perfusate for 60 minutes. EPIC was continued for postoperative 5 days. Results: All patients underwent resection of the lesions. Total pentonectomy was performed in 12 patients, while subtotal or partial peritonectomy was carried out in 14 according to the spread of carcinomatosis. Completeness of cytoreduction score of our patients was 0 in 18 patients, 1 in 6 patients and 2 in 2 patients. Major morbidity developed in 7 patients (27\%). CRS+HIPEC+EPIC yielded acceptable morbidity and mortality rates. Of the 26 patients, 20 (77\%) were alive without evidence of disease with a mean follow-up period of 13 6 months. Overall 1 year survival was 60\%. Conclusion: Cytoreductive approach combined with intraperitoneal chemotherapy prolongs survival in selected patients with peritoneal carcinomatosis (PC) with acceptable morbidity and mortality.
  • No Thumbnail Available
    Item
    HIF-1 alpha Levels in patients receiving chemoradiotherapy for locally advanced non-small cell lung carcinoma
    (ASSOC MEDICA BRASILEIRA, 2019-01-01) Afsar, Cigdem Usul; Uysal, Pelin
    AIM: To examine the relationship between treatment response and hypoxia-inducible factor-1 alpha (HIF-1 alpha) levels in patients with locally advanced non-small cell lung cancer (NSCLC) who received chemoradiotherapy (CRT). METHODS: Eighty patients with NSCLC were included in the study and treated at Acibadem Mehmet Ali Aydinlar University Medical Faculty. HIF-1 alpha levels were measured before and after CRT by the enzyme-linked immunosorbent assay (ELISA) method. RESULTS: Patients' stages were as follows
  • No Thumbnail Available
    Item
    Asymptomatic pancreatic body herniation complicated with periauricular squamous cell carcinoma
    (ELSEVIER SCIENCE BV, 2018-01-01) Yildiz, Isil
    Hiatus hernia is defined as herniation of the abdominal elements through the esophageal hiatus into the madiastinum. Type IV hiatal herniation is the rarest of all paraoesaphagial hernias. Herniation of pancreas is extremely rare. A 63-year-old male was admitted to the department of oncology with a periauricular squamous cell carcinoma (SCC). Abdominal CT was performed for organ metastasis. No metastasis was found, but hiatal herniation of the stomach along with the body of the pancreas into the thorax was observed. To our knowledge, this is the first case of herniated pancreatic body complicated with a carcinoma in the literature.