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Permanent URI for this collectionhttps://hdl.handle.net/11443/932
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Item Prostate cancer in Asia: A collaborative report(ELSEVIER SINGAPORE PTE LTD, 2014-01-01) Chen, Rui; Ren, Shancheng; Yiu, Ming Kwong; Fai, Ng Chi; Cheng, Wai Sam; Ian, Lap Hong; Naito, Seiji; Matsuda, Tadashi; Kehinde, Elijah; Kural, Ali; Chiu, Jason Yichun; Umbas, Rainy; Wei, Qiang; Shi, Xiaolei; Zhou, Liqun; Huang, Jian; Huang, Yiran; Xie, Liping; Ma, Lulin; Yin, Changjun; Xu, Danfeng; Xu, Kexin; Ye, Zhangqun; Liu, Chunxiao; Ye, Dingwei; Gao, Xin; Fu, Qiang; Hou, Jianquan; Yuan, Jianlin; He, Dalin; Pan, Tiejun; Ding, Qiang; Jin, Fengshuo; Shi, Benkang; Wang, Gongxian; Liu, Xiuheng; Wang, Dongwen; Shen, Zhoujun; Kong, Xiangbo; Xu, Wanhai; Deng, Yaoliang; Xia, Haibo; Cohen, Alexa N.; Gao, Xu; Xu, Chuanliang; Sun, Yinghao; Consortium, Chinese Prostate CancThe incidence of prostate cancer (PCa) within Asian population used to be much lower than in the Western populationItem Comparison of pediatric and adult antibiotic-associated diarrhea and Clostridium difficile infections(BAISHIDENG PUBLISHING GROUP INC, 2016-01-01) McFarland, Lynne Vernice; Ozen, Metehan; Dinleyici, Ener Cagri; Goh, ShanAntibiotic-associated diarrhea (AAD) and Clostridum difficile infections (CDI) have been well studied for adult cases, but not as well in the pediatric population. Whether the disease process or response to treatments differs between pediatric and adult patients is an important clinical concern when following global guidelines based largely on adult patients. A systematic review of the literature using databases PubMed (June 3, 1978-2015) was conducted to compare AAD and CDI in pediatric and adult populations and determine significant differences and similarities that might impact clinical decisions. In general, pediatric AAD and CDI have a more rapid onset of symptoms, a shorter duration of disease and fewer CDI complications (required surgeries and extended hospitalizations) than in adults. Children experience more community-associated CDI and are associated with smaller outbreaks than adult cases of CDI. The ribotype NAP1/027/BI is more common in adults than children. Children and adults share some similar risk factors, but adults have more complex risk factor profiles associated with more co-morbidities, types of disruptive factors and a wider range of exposures to C. difficile in the healthcare environment. The treatment of pediatric and adult AAD is similar (discontinuing or switching the inciting antibiotic), but other treatment strategies for AAD have not been established. Pediatric CDI responds better to metronidazole, while adult CDI responds better to vancomycin. Recurrent CDI is not commonly reported for children. Prevention for both pediatric and adult AAD and CDI relies upon integrated infection control programs, antibiotic stewardship and may include the use of adjunctive probiotics. Clinical presentation of pediatric AAD and CDI are different than adult AAD and CDI symptoms. These differences should be taken into account when rating severity of disease and prescribing antibiotics.Item Prevalence of Daytime Urinary Incontinence and Related Risk Factors in Primary School Children in Turkey(KOREAN UROLOGICAL ASSOC, 2014-01-01) Bolat, Deniz; Acar, Ismail Cenk; Zumrutbas, Ali Ersin; Eskicorapci, Saadettin; Sancak, Eyup Burak; Zencir, Mehmet; Turan, Tahir; Sinik, ZaferPurpose: Urinary incontinence is one of the major urinary symptoms in children and adolescents and can lead to major distress for the affected children and their parents. In accordance with the definitions of the Standardization Committee of the International Children's Continence Society, daytime urinary incontinence (DUI) is uncontrollable leakage of urine during the day. The aim of this cross-sectional study was to investigate the prevalence and associated risk factors of DUI in Turkish primary school children. Materials and Methods: The questionnaire, which covered sociodemographic variables and the voiding habits of the children, was completed by the parents of 2,353 children who were attending primary school in Denizli, a developing city of Turkey. The children's voiding habits were evaluated by use of the Dysfunctional Voiding and Incontinence Symptoms Score, which is a validated questionnaire. Children with a history of neurological or urological diseases were excluded. Results: The participation rate was 91.9\% (2,164 people). The overall prevalence of DUI was 8.0\%. The incidence of DUI tended to decrease with increasing age and was not significantly different between genders (boys, 8.8\%Item Breastfeeding, nutrition and type 1 diabetes: a case-control study in Izmir, Turkey(BMC, 2022-01-01) Cicekli, Ipek; Durusoy, RaikaBackground The relationship between infant breastfeeding and type 1 diabetes mellitus (DM) is unclear but it has been suggested that there may be a link between many environmental factors, including dietary antigens affecting diabetes epidemiology. The main objective of this study is to investigate nutritional risk factors, especially breastfeeding early in life that may be associated with the development of type 1 DM and to determine the relationship these factors have with the disease. Methods This research is a case-control study and was carried out in Ege University Children's Hospital in Izmir, Turkey between 13 January 2020 and 5 March 2020. A total of 246 children aged between 4 and 14 years were included in the study. The case group consisted of patients diagnosed with type 1 DM followed-up by Ege University Children's Hospital's Endocrinology Unit and the control group included non-diabetic children attending the same hospital's General Pediatric Outpatient Clinic. A structured questionnaire was created by the researchers after reviewing the literature related to nutritional and other risk factors for type 1 DM. The questionnaire was administered by interviewing the parents and it was related to the child, mother and family of the child. In this study, breastfeeding duration was defined as the total duration of breastfeeding and exclusive breastfeeding meant that the child received only breast milk from the mother. Results The mean age at diagnosis was 6.30 +/- 4.03 years for cases and 7.48 +/- 2.56 years for controls. We found that each monthly increase in exclusive breastfeeding duration provided a 0.83-fold (95\% CI 0.72, 0.96) decrease in the risk of type 1 DM. Introduction of cereals in the diet at the sixth month or earlier was associated with a 2.58-fold (95\% CI 1.29, 5.16) increased risk. Conclusions Determining the contribution of exclusive breastfeeding to the disease is important in establishing preventive policies. A longer duration of exclusive breastfeeding may be an important role in preventing the disease. This free intervention that truly works will be cost-effective. Future studies are needed to clarify the role of both exclusive and non-exclusive breastfeeding on the development of type 1 DM.