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    Soluble P-selectin as a potential diagnostic and prognostic biomarker for COVID-19 disease: A case-control study
    (PERGAMON-ELSEVIER SCIENCE LTD, 2021-01-01) Karsli, Emre; Sabirli, Ramazan; Altintas, Emel; Canacik, Omer; Sabirli, Gizem Tukenmez; Kaymaz, Buse; Kurt, Ozgur; Koseler, Aylin
    Introduction: To our knowledge, the diagnostic value of the sP-Selectin level in the diagnosis of COVID-19 disease has not yet been investigated. In this study, we aimed to assess this by evaluating the relationship between sPSelectin level and the clinical severity of COVID-19 infections. Methods: A total of 80 patients (50 with mild to moderate and 30 with severe COVID-19 pneumonia), and 60 nonsymptomatic healthy volunteers participated in the study. Following serum isolation, sP-Selectin levels were assessed by Enzyme-Linked Immunosorbent Assay (ELISA) method. Results: The serum sP-Selectin level was 1.7 ng/ml in the control group (1-3.78)