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    Validity and reliability of the measure yourself medical outcome profile 2 (MYMOP2) questionnaire among Turkish patients having anorectal disorders
    (AVES, 2019-01-01) Ersoy, Ozdal; Temel, Yasemin Ecem; Alptekin, Hasan Kerem
    Background/Aims: Measure Yourself Medical Outcome Profile 2 (MYMOP2) is a patient-generated outcome measure allowing patients to select the problems that are the most important to them and that they want to address, and it measures the effects of the problem from a wide range of health care interventions. This study aimed to translate the questionnaire into Turkish language (Turkish MYMOP-TMYMOP) and add this clinically useful measure to Turkish medical practice by assessing its validity and reliability. Materials and Methods: Fifty volunteers with anorectal disorders were prospectively included into the study. Each patient was enrolled into a pelvic floor training biofeedback program, specific to their anorectal symptomatology. The subjects were administered both the Nottingham Health Profile and the TMYMOP2 questionnaires before the treatment session (initial visit) and at the control follow-up visits (the first and second months, via e-mail or telephone calls). Results: The TMYMOP2 questionnaire was shown to be moderately valid (the Pearson correlation coefficient score between the total scores of the subgroups of the two questionnaires were 0.335 and 0.642, respectively, p<0.05) and highly reliable (the Cronbach's alfa coefficient score between the total scores of the subgroups of the two questionnaires were 0.77, 0.82, and 0.88 in the beginning and at the first and second month follow-up visits, respectively). Conclusion: The TMYMOP2 was shown to be a low-to-moderately valid and a highly reliable scale. Because it is brief and short to complete, it might be an important and free-to-use tool to measure the diseases, and it can enhance the patient-centered care within the Turkish health care context.
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    Self-perspective Versus Caregiver-perspective on Cognitive Impairment at Different Stages of the Alzheimer's Continuum
    (GALENOS PUBL HOUSE, 2022-01-01) Seckin, Mustafa; Ozturk, Gulcan; Dilmac, Ecem; Gurvit, Hakan
    Objective: To understand how the patients' and their study partners'/caregivers' perspectives on cognitive decline change at the subjective cognitive decline (SCD), mild cognitive impairment (MCI), and probable Alzheimer's disease (PRAD) stages of the Alzheimer's disease (AD) continuum. Materials and Methods: Twenty-three individuals with the diagnosis of SCD, 33 individuals with the diagnosis of MCI, and 17 individuals with the diagnosis of PRAD were included. A cognitive testing battery including the standardized mini-mental state examination (MMSE), digit span forward and backwards tests, and the semantic fluency test were administered to all patients. The cognitive function instrument (CFI) was used for the subjective assessment of cognitive decline. The same questions in the CFI were answered both by the patients (CFI-self report) and the study partners (CFI-partner report). Results: In the SCD and the MCI groups, the CFI-self report scores were higher than the CFI-partner report scores, whereas an opposite pattern was found in the PRAD group with higher CFI-partner report scores and lower CFI-self report scores. The CFI self report scores positively correlated with the MMSE scores in the PRAD group showing higher ratings in cognitively less impaired individuals, and vice versa. The CFI partner-report scores did not show a significant correlation with the MMSE scores in any of the groups, however a trend for a negative correlation was observed in the MCI group. Finally, the CFI-self report and partner report scores significantly correlated only in the MCI group. Conclusion: Report-based assessment of cognitive decline can be informative, particularly in the early stages of the AD continuum. However, the loss of insight in PRAD may mask the symptoms when the subjective cognitive assessment relies on the patients' perspective. The greatest concordance between the patients' and their partners' perspectives was evident in the MCI stage which represented a transitional period between SCD and PRAD.