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Subject: search.filters.subject.Chronic obstructive pulmonary disease

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    Immunization status in chronic obstructive pulmonary disease: A multicenter study from Turkey
    (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2019-01-01) Ozlu, Tevfik; Bulbul, Yilmaz; Aydin, Derya; Tatar, Dursun; Kuyucu, Tulin; Erboy, Fatma; Koseoglu, Handan Inonu; Anar, Ceyda; Sunnetcioglu, Aysel; Gulhan, Pinar Yildiz; Sahin, Unal; Ekici, Aydanur; Duru, Serap; Ulasli, Sevinc Sarinc; Kurtipek, Ercan; Gunay, Sibel; Okutan, O.; Yildiz, B. P.; Cetinkaya, P. D.; Arslan, S.; Cakmak, G.; Cirak, A. K.; Sarioglu, N.; Kocak, N. D.; Akturk, U. A.; Demir, M.; Kilic, T.; Dalli, A.; Hezer, H.; Altintas, N.; Acat, M.; Dagli, C. E.; Kargi, A.; Yakar, F.; Kirkil, G.; Baccioglu, A.; Gedik, C.; Intepe, Y. S.; Karadeniz, G.; Onyilmaz, T.; Saylan, B.; Baslilar, S.; Sariman, N.; Ozkurt, S.; Arinc, S.; Kanbay, A.; Yazar, E. E.; Yildirim, Z.; Kadioglu, E. E.; Gul, S.; Sengul, A.; Berk, S.; Dikis, O. S.; Kurt, O. K.; Arslan, Y.; Erol, S.; Korkmaz, C.; Balaban, A.; Erbay, Toru U.; Sogukpinar, O.; Uzaslan, E. K.; Babaoglu, E.; Bahadir, A.; Baris, S. A.; Ugurlu, A. O.; Ilgazli, A. H.; Fidan, F.; Kararmaz, E.; Guzel, A.; Alzafer, S.; Cortuk, M.; Hocanli, I.; Ortakoylu, M. G.; Erginel, M. S.; Yaman, N.; Erbaycu, A. E.; Demir, A.; Duman, D.; Tanriverdi, H.; Yavuz, M. Y.; Sertogullarindan, B.; Ozyurt, S.; Bulcun, E.; Yuce, G. D.; Sariaydin, M.; Ayten, O.; Bayraktaroglu, M.; Tekgul, S.; Erel, F.; Senyigit, A.; Kaya, S. B.; Ayik, S.; Yazici, O.; Akgedik, A.; Yasar, Z. A.; Hayat, E.; Kalpaklioglu, F.; Sever, F.; Sarac, P.; Ugurlu, E.; Kasapoglu, U. S.; Gunluoglu, G.; Demirci, N. Y.; Bora, M.; Talay, F.; Ozkara, B.; Yilmaz, M. U.; Yavsan, D. M.; Cetinoglu, E. D.; Balcan, M. B.; Ciftci, T.; Havan, A.; Gok, A.; Nizam, M.; Investigators, R.I.M.P.A.C.T. Study
    OBJECTIVE: The purpose of this study is to detect the prevalence and the factors associated with influenza and pneumococcal vaccination and outcomes of vaccination during 2013-2014 season in patients with chronic obstructive pulmonary disease (COPD) in Turkey. METHODS: This was a multicenter retrospective cohort study performed in 53 different centers in Turkey. RESULTS: During the study period, 4968 patients were included. COPD was staged as GOLD 1-2-3-4 in 9.0\%, 42.8\%, 35.0\%, and 13.2\% of the patients, respectively. Influenza vaccination rate in the previous year was 37.9\%
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    Evaluation of ghrelin and leptin in chronic obstructive pulmonary disease
    (WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2019-01-01) Uysal, Pelin; Uzun, Hafize
    OBJECTIVE: Recent studies suggest an important role for ghrelin and leptin in pathogenesis of inflammatory respiratory diseases. Therefore, the present study aimed to investigate ghrelin and leptin levels in the circulation that might be associated with the development of obstruction. METHODS: Stable chronic obstructive pulmonary disease (COPD) patients (n= 119) and matched healthy controls (n = 27) were recruited. The COPD patients were classified into four groups (A, B, C, and D) according to the Revised Global Initiative for Chronic Obstructive Lung Disease guidelines. RESULTS: Compared to controls, significantly decreased leptin and ghrelin levels were observed in all COPD patient groups. Plasma ghrelin concentration was higher in Group A (P < 0.001), Group B (P < 0.001), and Group C (P < 0.05) when compared with the Group D. Plasma leptin concentration was significantly decreased in Group D patients when compared with Group A (P < 0.001) and Group B (P< 0.001). Ghrelin levels were positively correlated with forced expiratory volume in 1 s (FEV1) (r= 0.822