WOS

Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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Subject: search.filters.subject.Disease free survival

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Now showing 1 - 3 of 3
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    Predictive Values of Systemic Inflammation Index in Prognosis of Patients with Laryngeal Cancer
    (KARE PUBL, 2020-01-01) Demir, Atakan; Alan, Ozkan; Surmeli, Mehmet
    Objectives: Laryngeal cancer is the most common cancer in head and neck cancer group, of which it constitutes 75\%. Squamous cell carcinoma (SCC) is the most common histological subtype. Systemic or local inflammation is a well known promotor for cancer development and progression. Systemic immune inflammation index (S II) has been reported as an independent prognostic parameter in various cancers. We aimed to evaluate the capability of SII in predicting the risk of recurrence in patients with operable laryngeal cancer. Methods: We retrospectively collected the data of 100 laryngeal SCC patients who underwent surgery between 2016 and 2018. Neutrophil, lymphocyte, and platelet (Plt) counts were recorded. The SII was calculated as follows: SII= Neutrophile counts {*}platelet counts/lymphocyte counts. Results: SI index was found to be an independent prognostic factor as affecting disease recurrence (p<0.05). We found that patients with SII >891 had a risk of disease recurrence of approximately three times more than patients with SII = <891.78 (HR: 3.06 (95\% CI: 3.42-132.64). Conclusion: This was the first study to demonstrate that preoperative SI index is a simple and powerful independent predictive index that predicts the risk of disease recurrence in patients with laryngeal cancer.
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    The role of red cell distribution width in the locoregional recurrence of laryngeal cancer
    (ASSOC BRASILEIRA OTORRINOLARINGOLOGIA \& CIRURGIA CERVICOFACIAL, 2019-01-01) Bozkurt, Gulpembe; Korkut, Arzu Yasemin; Soytas, Pinar; Dizdar, Senem Kurt; Erol, Zeynep Nur
    Introduction: Although the red cell distribution width has been reported as a reliable predictor of prognosis in several types of cancer, to our knowledge few reports have focused on the prognostic value of red cell distribution width in laryngeal carcinoma. Objective: We aimed to explore whether the pretreatment red cell distribution width predicted recurrence in laryngeal cancer patients is a simple, reproducible, and inexpensive prognostic biomarker. Methods: All laryngeal cancer patients who underwent curative surgery (n= 132) over a 7 year study period were evaluated. Data on demographics, primary tumor site, T-stage, N-stage, histological features (differentiation
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    Prognostic significance of primary tumor localization in stage II and III colon cancer
    (BAISHIDENG PUBLISHING GROUP INC, 2018-01-01) Sakin, Abdullah; Arici, Serdar; Secmeler, Saban; Can, Orcun; Geredeli, Caglayan; Yasar, Nurgul; Demir, Cumhur; Demir, Osman Gokhan; Cihan, Sener
    AIM To investigate the effects of tumor localization on disease free survival (DFS) and overall survival (OS) in patients with stage I -III colon cancer. METHODS This retrospective study included 942 patients with stage. and. colon cancer, which were followed up in our clinics between 1995 and 2017. The tumors from the caecum to splenic flexure were defined as right colon cancer (RCC) and those from splenic flexure to the sigmoid colon as left colon cancer (LCC). RESULTS The median age of the patients was 58 years (range: 19-94 years). Male patients constituted 54.2\%. The rates of RCC and LCC were 48.4\% (n = 456) and 51.6\% (n = 486), respectively. During the median follow-up of 90 mo (range: 6-252 mo), 14.6\% of patients developed recurrence and 9.1\% of patients died. In patients with stage. and. disease with or without adjuvant therapy, DFS was similar in terms of primary tumor localization (stage.