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Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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Subject: search.filters.subject.Obstructive sleep apnea

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    Intra-rater and Inter-rater consistency of drug induced sleep endoscopy
    (DEOMED PUBL, ISTANBUL, 2019-01-01) Kilavuz, Ahmet Erdem; Bayram, Ali Alper
    Objective: Drug induced sleep endoscopy (DISE) is a valuable tool which is used in the diagnosis of obstructive sleep apnea (OUA). The aim of this study is to evaluate inter-rater and intra-rater consistency of DISE. Methods: 36 OSA patients with Apnea-hypopne index>5 included in this study. DISE was performed and recorded digitally for all patients, by the first author (OA1). VOTE scores were noted to procedure report in patients' charts. Video records of DISE were blindly evaluated six months after the last procedure, by observer 1 for the second time (OA2) and by observer 2 (OB) for the first time. DISE was evaluated by using VOTE classification. OA1 and OA2 scores were compared to determine intra-rater reliability and OA2 and OB scores were compared to determine inter-rater reliability. Results: Inter-rater consistency of DISE was poor to good. Highest consistency rate was found in velum at anteroposterior configuration, while the lowest was found in the same level at lateral configuration. Intra-rater consistency of DISE was moderate to excellent. Highest consistency rate was found in epiglottis at lateral configuration, while the lowest was found in oropharynx level. Conclusion: OSA is condition with possible serious complications. DISE is a tool that could change the course of treatment in OSA. The validity of DISE is quite acceptable although a golden standard classification tool could enable us to ``speak the exact same language{''} and will surely increase the diagnostic success of DISE.
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    Defining of the Relationship Between Lung Volumes, Airway Resistance and the Apnea-Hypopnea Index
    (GALENOS PUBL HOUSE, 2018-01-01) Afsar, Gulgun Cetintas; Sarac, Sema; Babalik, Aylin; Calisir, Haluk Celalettin
    Objective: Obstructive Sleep Apnea syndrome (OSAS) is characterized by recurrent complete or partial narrowing of the upper respiratory tract during sleep and frequently a decrease in blood oxygen saturation. Upper respiratory tract gap is determined by the balance between collapsing effect of negative intraluminal pressure during inspiration and upper airway dilator muscle activity. In this study, we aimed to describe the relationship among the lung volumes and airway resistance, which are not thought to be directly taken a part in OSAS pathogenesis, and OSAS cases at different severity. Materials and Methods: Our study has been conducted on 105 cases 26 (24.8\%) of which are female and 79 (75.2\%) male who were applied polisomnography in the Ministry of Health Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital, Chest Disease Clinic between January 2008 and May 2008. Whole body plethysmography was performed to cases which filled patient information form containing identity informations, body mass index (BMI), neck circumference, additional disease situation, smoking anamnesis and Epworth sleepiness scale (ESS). Pulmonary function tests, lung volumes and airway resistances were recorded by looking at the expected \% values for age, color and weight. Results: Patients were divided into 4 groups according to apnea-hypopnea index
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    Obstructive Sleep Apnea and Cancer
    (GALENOS PUBL HOUSE, 2016-01-01) Demir, Ceyda Erel Kirisoglu
    Obstructive sleep apnea (OSA) is a common disorder which is associated with increased morbidity and mortality. There is growing evidence that patients with OSA have higher incidence of cancer, accelerated progression and cancer mortality. Intermittent hypoxia, oxidative stress and sleep fragmentation are hold responsible for cancer development.