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    Serum Proteomic Changes in Dogs with Different Stages of Chronic Heart Failure
    (MDPI, 2022-01-01) Saril, Ahmet; Kocaturk, Meric; Shimada, Kazumi; Uemura, Akiko; Akgun, Emel; Levent, Pinar; Baykal, Ahmet Tarik; Prieto, Alberto Munoz; Agudelo, Carlos Fernando; Tanaka, Ryou; Ceron, Jose Joaquin; Koch, Jorgen; Yilmaz, Zeki
    Simple Summary Canine MMVD is a progressive chronic disease with variable clinical signs, with some patients remaining completely asymptomatic while others develop CHF. Here, the aims of the pilot study were to evaluate serum proteins by proteomic analysis in dogs at different stages of chronic heart failure (CHF) due to degenerative mitral valve disease (MMVD), and how these proteins can change after a conventional treatment. Study revealed 157 different proteins