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Permanent URI for this collectionhttps://hdl.handle.net/11443/932

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Subject: search.filters.subject.fibroblast

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    Partial healing effects of St. John's wort oil on the rat excisional wound model
    (MARMARA UNIV, FAC MEDICINE, 2022-01-01) Atsu, Ayse Nilhan; Bilgic, Tayfun; Kayhan, Cavit Kerem; Saglam, Zumrut Mine Isik; Caf, Nazli
    Objective: St. John's wort (SJW) oil (Hypericum perforatum) has been used for its immunomodulatory and anti-inflammatory effects. Several studies have shown the efficacy of SJW on wound healing. The aim of this study is to assess the effectiveness of SJW using a combination of biochemical, histopathological and laser Doppler evaluations. Materials and Methods: Sixteen young Wistar albino rats were used as case and control groups (having 8 in each group). After anesthesia protocol, 6 mm punch biopsy was taken from six separate sites on the rats' dorsal skin. Three wounds were stitched (closed wounds)