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    The Influence of Diagnosis, Age, and Gender on Surgical Outcomes in Patients With Adult Spinal Deformity
    (SAGE PUBLICATIONS LTD, 2018-01-01) Ayhan, Selim; Yuksel, Selcen; Nabiyev, Vugar; Adhikari, Prashant; Villa-Casademunt, Alba; Pellise, Ferran; Sanchez Perez-Grueso, Francisco; Alanay, Ahmet; Obeid, Ibrahim; Kleinstueck, Frank; Acaroglu, Emre; Grp, European Spine Study
    Study Design: Retrospective review of prospectively collected data from a multicentric database. Objectives: To determine the clinical impact of diagnosis, age, and gender on treatment outcomes in surgically treated adult spinal deformity (ASD) patients. Methods: A total of 199 surgical patients with a minimum follow-up of 1 year were included and analyzed for baseline characteristics. Patients were separated into 2 groups based on improvement in health-related quality of life (HRQOL) parameters by minimum clinically important difference. Statistics were used to analyze the effect of diagnosis, age, and gender on outcome measurements followed by a multivariate binary logistic regression model for these results with statistical significance. Results: Age was found to affect SF-36 PCS (Short From-36 Physical Component Summary) score significantly, with an odds ratio of 1.017 (unit by unit) of improving SF-36 PCS score on multivariate analysis (P < .05). The breaking point in age for this effect was 37.5 years (AUC = 58.0, P = .05). A diagnosis of idiopathic deformity would increase the probability of improvement in Oswestry Disability Index (ODI) by a factor of 0.219 and in SF-36 PCS by 0.581 times (P < .05). Gender was found not to have a significant effect on any of the HRQOL scores. Conclusions: Age, along with a diagnosis of degenerative deformity, may have positive effects on the likelihood of improvement in SF-36 PCS (for age) and ODI (for diagnosis) in surgically treated patients with ASD and the breaking point of this effect may be earlier than generally anticipated. Gender does not seem to affect results. These may be important in patient counseling for the anticipated outcomes of surgery.
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    Influence of Gender on Inhaler Technique
    (DAEDALUS ENTERPRISES INC, 2020-01-01) Ocakli, Birsen; Ozmen, Ipek; Tuncay, Eylem Acarturk; Gungor, Sinem; Ozalp, Aylin; Yasin, Yesim; Adiguzel, Nalan; Gungor, Gokay; Karakurt, Zuhal
    This study was designed to evaluate the influence of gender on the inhaler technique of subjects on inhaler therapy and to determine the factors predicting the correct inhaler technique and a change of inhaler device. METHODS: A total of 568 adult subjects (276 male, 292 female) on inhaler therapy were included in this cross-sectional, observational study. Data on sociodemographic characteristics, inhaler therapy, subject-reported difficulties, and technician-reported errors in inhaler technique were recorded. RESULTS: A change of inhaler device was noted in 71.0\% of male subjects and 77.4\% of female subjects, and this was based on the physicians' decision in most cases (41.7\% and 51.7\%, respectively). A higher percentage of female subjects reported difficulties with using inhalers (63.7\% vs 40.6\%, P < .001). Overall, having received training on the inhaler technique was associated with a higher likelihood of correct inhaler technique (odds ratio 12.56, 95\% CI 4.44-35.50, P < .001) and a lower risk of device change (odds ratio 0.46, 95\% CI 0.27-0.77, P = .004). CONCLUSIONS: Errors in the inhaler technique, including inhalation maneuvers and device handling, were common in subjects on inhaler therapy. Subject-reported difficulties with using inhalers were more prevalent among female subjects, whereas errors in the inhaler technique identified by direct observation were similarly high in both genders. Overall, a lack of training on the inhaler technique predicted a higher likelihood of errors in the inhaler technique and a change of inhaler device.
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    Glenoid Morphology and Related Parameters in Turkish Society
    (CUREUS INC, 2022-01-01) Karademir, Goekhan; Aslan, Omer
    Introduction Glenoid morphology may vary in different ethnic groups. Detection of these differences may be important in preoperative planning, especially in reverse shoulder arthroplasty. In this study, we investigated the mean glenoid size and retroversion in Turkish society and their relationship with the dominant side, gender, height, weight, and body mass index (BMI). Materials and methods Between 2019 and 2021, 102 shoulders of 51 patients (24 females/27 males, 51 left/51 right) who were included in shoulder joint imaging during thorax CT scanning were examined. Those with glenoid fracture, arthrosis, shoulder surgery or deformity, or younger than 18 years of age were not included in the study. The mean age was 41.69 (range: 18-73) years. Glenoid anterior-posterior diameter (D) and glenoid version (GV) were measured in axial slices, and glenoid height (H) was measured in coronal slices. The correlation of these parameters with gender, height, weight, and dominant side was examined. Results Mean D was 25.79 +/- 4.44 mm, mean H was 29.08 +/- 4.08 mm, and mean GV was-0.99 degrees +/- 0.92 degrees. The mean height of the patients was 162 +/- 16.23 cm and the mean weight was 71.9 +/- 15.36 kg. The glenoid diameter and height were smaller in females, however, no statistically significant difference was found in the glenoid version (p<0.01, p<0.01, and p=0.92). The glenoid on the dominant side was statistically significantly more retroverted, whereas D and H were not associated with dominance (p<0.01, p=0.9, and p=0.98). It was found that the glenoid sizes were very highly correlated with the patient's height, and it was highly correlated with the patient's weight (p<0.01 and p<0.01). On the other hand, height and weight were not correlated with the glenoid version (p=0.47 and p=0.81, respectively). There was no statistically significant relationship between BMI and glenoid sizes and glenoid version (p=0.14 and p=0.46, respectively). Conclusions Females in Turkish society had small glenoid sizes. Male gender, height, and weight were positively correlated with large glenoids. The glenoid was more retroverted on the dominant side. These findings should be considered in preoperative planning in Turkish society.
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    Age-Related Changes in Corneal Epithelial Thickness Measured with an Ultrasound Pachymeter
    (DOVE MEDICAL PRESS LTD, 2022-01-01) Colakoglu, Ahmet; Cosar, Cemile Banu
    Background: There is increasing research on the aging process of the cornea and its effect on the corneal parameters measured objectively. Nevertheless, the association of corneal epithelial thickness (CET) with age has yet to be fully illustrated.Purpose: We aimed to measure CET in healthy subjects to determine its age-related variation by using an ultrasound device. Patients and Methods: A total of one hundred and three subjects were enrolled in this study and grouped according to age: Group < 30 years, 31-40 years, 41-50 years, 51-60 years, 61-70 years, and > 71 years. The CET and total central corneal thickness (CCT) of each subject were measured by the Sonogage Corneo-Gage Plus 2 (Cleveland, Ohio) ultrasound pachymeter. The relationships between thickness values, laterality, age groups, and gender were analyzed using the Jonckheere-Terpstra test. The Partial correlation test was employed to assess the effect of age on the CET and CCT. Results: The mean CET was 47.88 +/- 1.15 mu m, with no statistically significant gender-related difference between right and left eyes. In addition, the CCT difference detected between female and male eyes was insignificant. The difference in mean CET across age groups was statistically significant (p =0.029). The difference in mean CET of left eyes across age groups was statistically significant (p=0.031). The mean CET and left CET of the oldest group were significantly thinner than the younger groups.Conclusion: Ultrasound pachymeter of the corneal epithelium demonstrated that there was no correlation between age and CCT, or gender. The CET becomes thinner with age in the central zone in both genders and there is no difference between males and females. Based on these results, age has a negative effect on CET. These findings could offer further insight into age-related changes in the cornea.