Araştırma Çıktıları

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    Relationship between disease severity and serum IL-6 levels in COVID-19 anosmia
    (W B SAUNDERS CO-ELSEVIER INC, 2021-01-01) Sanli, Deniz Esin Tekcan; Altundag, Aytug; Kandemirli, Sedat Giray; Yildirim, Duzgun; Sanli, Ahmet Necati; Saatci, Ozlem; Kirisoglu, Ceyda Erel; Dikensoy, Oner; Murrja, Edvin; Yesil, Atakan; Bastan, Serdar; Karsidag, Tamer; Akinci, Ibrahim Ozkan; Ozkok, Sezen; Yilmaz, Eren; Tuzuner, Filiz; Kilercik, Meltem; Ljama, Taner
    Background: An association between IL-6 levels and cytokine storm syndrome in COVID-19 patients has been suggested. Cases with higher IL-6 levels have more rapid progression and a higher complication rate. On the other hand, COVID-19 cases with anosmia have a milder course of the disease. Objective: We aimed to investigate whether there is a relationship between serum IL-6 levels and presence of anosmia in COVID-19 patients. Methods: Patients with a confirmed diagnosis of COVID-19 based on laboratory (PCR) were stratified into two groups based on presence of olfactory dysfunction (OD). In all cases with and without anosmia
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    Human Metapneumovirus Infection in Adults as the Differential Diagnosis of COVID-19
    (GALENOS YAYINCILIK, 2021-01-01) Dogan, Lerzan; Akinci, Canan; Sarikaya, Zeynep Tugce; Kaya, Hande Simten Demirel; Zengin, Rehile; Mammadov, Orkhan; Ilksoz, Aylin; Ozdemir, Ilkay Kisa; Eren, Meltem Yonca; Afsar, Nazire; Kocagoz, Sesin; Akinci, Ibrahim Ozkan
    Human metapneumovirus (HMPV) is a respiratory tract virus identified 18 years prior to severe acute respiratory syndrome coronavirus-2. Both viruses cause acute respiratory failure characterised by a rapid onset of widespread inflammation in the lungs with clinical symptoms similar to those reported for other viral respiratory lung infections. HMPV, more generally known as childhood viral infection, causes mild and self-limiting infections in the majority of adults, but clinical courses can be complicated in risky groups and associated morbidity and mortality are considerable. Moreover, adults are not regularly screened for HMPV and the prevalence of adult HMPV infections in Turkey is unknown, with previous reports in the paediatric population. This should always be kept in mind during the coronavirus disease-2019 pandemic, particularly when neurological complications are added to respiratory findings. In our study, two adult cases of HMPV pneumonia and encephalitis have been recorded.
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    Plasmapheresis treatment in COVID-19-related autoimmune meningoencephalitis: Case series
    (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2020-01-01) Dogan, Lerzan; Kaya, Dilaver; Sarikaya, Tugce; Zengin, Rehile; Dincer, Alp; Akinci, Ibrahim Ozkan; Afsar, Nazire
    Severe SARS-CoV-2 (COVID-19) infection has the potential for a high mortality rate. In this paper, we report the results of plasmapheresis treatment in a series of severely ill patients with COVID-19-related autoimmune meningoencephalitis in the Intensive Care Unit (ICU).