Araştırma Çıktıları

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    Impact of diabetes mellitus on urinary continence after holmium laser enucleation of the prostate due to lower urinary tract symptoms: a retrospective study
    (POLISH UROLOGICAL ASSOC, 2021-01-01) Acikgoz, Onur; Yilmaz, Mehmet; Aybal, Halil Cagri; Yilmaz, Sercan; Gazer, Eymen; Yalcin, Serdar; Duvarci, Mehmet; Kaya, Engin; Miernik, Arkadiusz; Tunc, Lutfi
    Introduction Diabetes mellitus (DM) is known as a risk factor of stress urinary incontinence after Holmium laser enucleation of the prostate (HoLEP). We aimed to compare the postoperative continence status of patients with and without DM, after HoLEP surgery. Material and methods A total of 214 patients who underwent HoLEP between January 2017 and January 2020 were retrospectively assessed. Functional outcomes, perioperative total operation time (TOT) (min), enucleation time (ET)(min), enucleation efficiency (EE)(g/min), enucleated tissue weight (ETW)(g), morcellation efficiency (ME)(g/min), morcellation time (MT)(min), continence status, intraoperative and postoperative complications according to Clavien-Dindo classification were recorded. Results A total of 96 patients had DM additional to benign prostate hyperplasia (BPH) (Group 1), while 118 patients had only benign prostate hyperplasia without DM (Group 2). When comparing preoperative and postoperative functional outcomes, a statistically significant improvement was observed in both groups from baseline to the 1st and 6th month follow-up (p <= 0.001). There were no statistically significant differences between groups in postoperative stress urinary incontinence at postoperative months 1 and 6 (1.7\% vs 2.1\%, p = 1 and 0.8\% vs 1\%, p = 1
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    Laser enucleation for prostates larger than 100 mL: Comparison of HoLEP and ThuLEP
    (WILEY, 2021-01-01) Kaya, Engin; Yilmaz, Sercan; Acikgoz, Onur; Aybal, Halil Cagri; Yilmaz, Mehmet; Gazel, Eymen; Yalcin, Serdar; Suarez-Ibarrola, Rodrigo; Tunc, Lutfi
    Recently, with the advancements in laser technology, Holmium laser enucleation of the prostate (HoLEP) and Thulium laser enucleation of the prostate (ThuLEP) have come to the fore in the surgical treatment of benign prostatic hyperplasia (BPH). We aimed to evaluate and compare the outcomes of HoLEP and ThuLEP in patients with >100 ml prostate volume. Patients who underwent HoLEP and ThuLEP between July 2017 and March 2020 were reviewed retrospectively. The patients were divided into two groups as HoLEP (Group 1, n = 121) and ThuLEP (Group 2, n = 104). Perioperative parameters, functional outcomes, continence status, intra and post-operative complications were compared between groups in the post-operative 1st and 6th month. No significant difference was found in terms of total laser energy (TLE), morcellation efficiency (ME), enucleated tissue weight (ETW), complication rates (CR) and continence status of patients between both groups (p > .05). In favour of ThuLEP group, there were statistically significant differences regarding total operation time (TOT), laser efficiency (LE), enucleation time (ET) and enucleation efficiency (EE) between groups (p <= .05). HoLEP and ThuLEP can be used safely and effectively in prostates larger than 100 ml.
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    The role of laparoscopic experience on the learning curve of HoLEP surgery: A questionnaire-based study
    (AVES, 2020-01-01) Gazel, Eymen; Kaya, Engin; Yalcin, Serdar; Tokas, Theodoros; Yilmaz, Sercan; Aybal, Halil Cagri; Aydogan, Tahsin Batuhan; Tunc, Lutfi
    Objective: Holmium laser enucleation of the prostate (HoLEP) is an established method for treating benign prostatic obstruction. Nonetheless, its steep learning curve limits its wide distribution. The purpose of the present study was to demonstrate the impact of laparoscopic experience on HoLEP learning curve by evaluating the association between learning curves of surgeons performing both laparoscopy and HOLEP surgery. Material and methods: A questionnaire was prepared to identify surgeon's experience on laparoscopy and HoLEP, as well as their learning curves. This questionnaire was then distributed via e-mail to 110 urologists who are actively involved in endourology/laparoscopy. Results: Of the 110 urologists, 80 (72.7\%) responded and completed the questionnaire. Of the 80 surgeons, 47 (58.8\%) reported that they had completed the HoLEP learning curve with <20 cases. Moreover, 33 (41.2\%) reported that they were able to complete the learning curve by performing >20 cases. Completion of the HoLEP learning curve in <20 cases was reached at 1.3\%, 13.8\%, and 43.8\% by beginner, moderate skilled, and experienced laparoscopists, respectively (p<0.001). Conclusion: Laparoscopic experience appears to be beneficial for surgeons while learning HoLEP. Highly experienced laparoscopic surgeons have a shorterHOLEP learning curve.
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    Impact of metabolic syndrome on pre- and postoperative parameters in patients undergoing a HoLEP surgery
    (AVES, 2019-01-01) Aydogan, Tahsin Batuhan; Kaya, Engin; Gazel, Eymen; Yalcin, Serdar; Aybal, Halil Cagri; Tunc, Lutfi
    Objective: We aimed to investigate the safety and success of the holmium laser enucleation of prostate (HoLEP) surgery in patients with metabolic syndrome (MS) versus those without MS who have similar prostate sizes. Material and methods: Data from 120 patients who underwent HoLEP by a single surgeon between November 2015 and January 2018 were prospectively analyzed. Group 1 (n=40) and Group 2 (n=80) consisted of patients with and without MS, respectively. Preoperative-and postoperative third month control variables that were compared between the groups included hemoglobin (Hb) level