Araştırma Çıktıları

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Author: search.filters.author.Babalik, Aylin

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    Plasma Concentrations of Isoniazid and Rifampin Are Decreased in Adult Pulmonary Tuberculosis Patients with Diabetes Mellitus
    (AMER SOC MICROBIOLOGY, 2013-01-01) Babalik, Aylin; Ulus, Ismail Hakki; Bakirci, Nadi; Kuyucu, Tulin; Arpag, Huseyin; Dagyildizi, Lale; Capaner, Esen
    Plasma isoniazid and rifampin concentrations, but not pyrazinamide and ethambutol concentrations, were decreased by about 50\% (P < 0.05) in diabetic pulmonary tuberculosis patients. The prevalences of subnormal plasma isoniazid, rifampin, pyrazinamide, and ethambutol concentrations were 49\% or 100\% (P < 0.01), 66\% or 100\% (P < 0.05), 30\% or 50\% (P = 0.198), and 32\% or 21\% (P = 0.742) in nondiabetic or diabetic tuberculosis patients, respectively. These data show that plasma concentrations of isoniazid and rifampin were greatly reduced in diabetic tuberculosis patients.
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    Defining of the Relationship Between Lung Volumes, Airway Resistance and the Apnea-Hypopnea Index
    (GALENOS PUBL HOUSE, 2018-01-01) Afsar, Gulgun Cetintas; Sarac, Sema; Babalik, Aylin; Calisir, Haluk Celalettin
    Objective: Obstructive Sleep Apnea syndrome (OSAS) is characterized by recurrent complete or partial narrowing of the upper respiratory tract during sleep and frequently a decrease in blood oxygen saturation. Upper respiratory tract gap is determined by the balance between collapsing effect of negative intraluminal pressure during inspiration and upper airway dilator muscle activity. In this study, we aimed to describe the relationship among the lung volumes and airway resistance, which are not thought to be directly taken a part in OSAS pathogenesis, and OSAS cases at different severity. Materials and Methods: Our study has been conducted on 105 cases 26 (24.8\%) of which are female and 79 (75.2\%) male who were applied polisomnography in the Ministry of Health Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital, Chest Disease Clinic between January 2008 and May 2008. Whole body plethysmography was performed to cases which filled patient information form containing identity informations, body mass index (BMI), neck circumference, additional disease situation, smoking anamnesis and Epworth sleepiness scale (ESS). Pulmonary function tests, lung volumes and airway resistances were recorded by looking at the expected \% values for age, color and weight. Results: Patients were divided into 4 groups according to apnea-hypopnea index
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    Biomass smoke exposure as a serious health hazard for women
    (TURKISH ASSOC TUBERCULOSIS \& THORAX, 2013-01-01) Babalik, Aylin; Bakirci, Nadi; Taylan, Mahsuk; Bostan, Leyla; Kiziltas, Sule; Basbug, Yelda; Calisir, Haluk C.
    Introduction: Lung diseases caused by biomass exposure cause a significant health hazard particularly amongst women. The present study was designed to investigate biomass exposure in women suffering from lung disease. Materials and Methods: A total of 100 women {[} mean (SD) age: 55.13 (17.65) years] hospitalized for chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, tuberculosis or interstitial lung disease were included in this study conducted between September 2008-March 2009 in three chest disease clinics at Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital. Data collection on biomass exposure was based on application of hospital-based survey questionnaire including items on occupation, level of education, place of birth (location, region), exposure to biomass fuel fumes for heating and cooking purposes (animal dung, wood, charcoal, dried plant) and years of exposure with animal dung, wood, charcoal, dried plant. Results: COPD in 22\% patients, lung carcinoma in 12\%, bronchitis in 8\%, tuberculosis in 26\%, and interstitial lung disease in 17\% were the diagnosis for hospitalization. The most identified occupation was housewifery 86\%. Active, former and nonsmokers composed 6\%, 22\% and 72\% of the population. Birth place was village in 67\% patients while districts in 9\%. According to regional distribution, the most common place of birth was Central Anatolia region in (29\%). Exposure to biomass fuels was identified in all of patients including wood (92\%), animal dung (30\%), charcoal (23\%), and dry plant (23\%). Mean (SD) years of exposure was identified to be 52.6 (17.9) years for wood, 40.8 (17.9) years for animal dung, 48.1 (20.8) years for dry plant and 38.5 (21.4) years for charcoal. The most common type of biomass exposure was wood in village (97\%), city (79\%) and county (89\%). Conclusion: Findings indicating impact of biomass exposure in women seem to emphasize the need for analytic epidemiologic studies assessment measuring biomass exposure levels-particularly for women and young children.