Araştırma Çıktıları

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Author: search.filters.author.Barkan, GulizSubject: search.filters.subject.cytology

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    Cytologic grading of primary malignant salivary gland tumors: A blinded review by an international panel
    (WILEY, 2020-01-01) Johnson, Daniel N.; Onenerk, Mine; Krane, Jeffrey F.; Rossi, Esther Diana; Baloch, Zubair; Barkan, Guliz; Bongiovanni, Massimo; Callegari, Fabiano; Canberk, Sule; Dixon, Glen; Field, Andrew; Griffith, Christopher C.; Jhala, Nirag; Jiang, Sara; Kurtycz, Daniel; Layfield, Lester; Lin, Oscar; Maleki, Zahra; Perez-Machado, Miguel; Pusztaszeri, Marc; Vielh, Philippe; Wang, He; Zarka, Matthew A.; Faquin, William C.
    Background Fine needle aspiration (FNA) is commonly used for the preoperative evaluation of salivary gland tumors. Tumor grade is a key factor influencing clinical management of salivary gland carcinomas (SGCs). To assess the ability to grade nonbasaloid SGCs in FNA specimens, an international panel of cytopathologists convened to review and score SGC cases. Methods The study cohort included 61 cases of primary SGC from the pathology archives of 3 tertiary medical centers. Cases from 2005 to 2016 were selected, scanned, and digitized. Nineteen cytopathologists blinded to the histologic diagnosis reviewed the digitized cytology slides and graded them as low, high, or indeterminate. The panelists' results were then compared to the tumor grades based on histopathologic examination of the corresponding resection specimens. Results All but 2 of the 19 (89.5\%) expert panelists review more than 20 salivary gland FNAs per year