Araştırma Çıktıları

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    Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society
    (PUBLIC LIBRARY SCIENCE, 2019-01-01) Koc, Esin; Demirel, Nihal; Bas, Ahmet Yagmur; Isik, Dilek Ulubas; Hirfanoglu, Ibrahim Murat; Tunc, Turan; Sari, Fatma Nur; Karatekin, Guner; Ozdemir, Ramazan; Altunhan, Huseyin; Cetinkaya, Merih; Ozcan, Beyza; Ozkiraz, Servet; Calkavur, Sebnem; Tekgunduz, Kadir Serafettin; Tastekin, Ayhan; Ozlu, Ferda; Ozyurt, Banu Mutlu; Ozdemir, Ahmet; Cetinkaya, Bilin; Demirelli, Yasar; Koklu, Esad; Celik, Ulker; Tarakci, Nuriye; Armangil, Didem; Okulu, Emel; Narter, Fatma; Mutlu, Birgul; Mert, Mustafa Kurthan; Bulbul, Ali; Asker, Huseyin Selim; Uygur, Ozgun; Uslu, Ilker Sait; Ertugrul, Sabahattin; Aydemir, Cumhur; Celik, Hasan Tolga; Kucuktasci, Kazim; Arslan, Selda; Ergin, Hacer; Zenciroglu, Aysegul; Yurttutan, Sadik; Orman, Aysen; Tuncer, Oguz; Yasa, Beril; Acunas, Betul; Takci, Sahin; Gokmen, Zeynel; Ozkan, Hilal; Comert, Serdar; Ustun, Nuran; Mutlu, Mehmet; Bayraktar, Bilge Tanyeri; Bilgin, Leyla; Tuzun, Funda; Aydemir, Ozge; Gursoy, Tugba; Akdag, Arzu; Memisoglu, Asli; Can, Emrah; Terek, Demet; Beken, Serdar; Turan, Ozden; Guzoglu, Nilufer; Ors, Rahmi; Kale, Yusuf; Hekimoglu, Berna; Aylanc, Hakan; Eroglu, Funda; Sahin, Suzan; Konak, Murat; Sarici, Dilek; Kilic, Ilknur; Hakan, Nilay
    Objective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of.1500 g were collected for infants who survived. Results Data from 69 NICUs were obtained. The mean birth weight and gestational age were 1137 +/- 245 g and 29 +/- 2.4 weeks, respectively. During the study period, 78\% of VLBW infants survived to discharge and 48\% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7\% of infants, necrotizing enterocolitis in 9.1\%, blood culture proven late-onset sepsis (LOS) in 21.1\%, blood culture negative LOS in 21.3\%, severe intraventricular hemorrhage in 5.4\% and severe retinopathy of prematurity in 11.1\%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8\% of infants. Antenatal steroids were administered to 42.9\% of mothers. Conclusion The present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.
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    The prevalence and diagnostic criteria of health-care associated infections in neonatal intensive care units in Turkey: A multicenter point- prevalence study
    (ELSEVIER TAIWAN, 2021-01-01) Demirdag, Tugba Bedir; Koc, Esin; Tezer, Hasan; Oguz, Suna; Satar, Mehmet; Saglam, Ozge; Uygun, Saime Sunduz; Onal, Esra; Hirfanoglu, Ibrahim Murat; Tekgunduz, Kadir; Oygur, Nihal; Bulbul, Ali; Zubarioglu, Adil Umut; Ustun, Nuran; Unal, Sezin; Aygun, Canan; Karagol, Belma Saygili; Zenciroglu, Aysegul; Oncel, M. Yekta; Saglik, Adviye Cakil; Okulu, Emel; Terek, Demet; Narli, Nejat; Aliefendioglu, Didem; Gursoy, Tugba; Unal, Sevim; Turkmen, Munevver Kaynak; Narter, Fatma Kaya; Ciftdemir, Nukhet Aladag; Beken, Serdar; Cakir, Salih Cagri; Yigit, Sule; Coban, Asuman; Ecevit, Ayse; Celik, Yalcin; Kulali, Ferit
    Background: Healthcare-acquired infections (HAIs) in the neonatal period cause substantial morbidity, mortality, and healthcare costs. Our purpose was to determine the prevalence of HAIs, antimicrobial susceptibility of causative agents, and the adaptivity of the Centres for Disease Control and Prevention (CDC) criteria in neonatal HAI diagnosis. Methods: A HAI point prevalence survey was conducted in the neonatal intensive care units (NICUs) of 31 hospitals from different geographic regions in Turkey. Results: The Point HAI prevalence was 7.6\%. Ventilator-associated pneumonia (VAP) and central line-associated bloodstream infections (CLABSI) and late onset sepsis were predominant. The point prevalence of VAP was 2.1\%, and the point prevalence of CLABSI was 1.2\% in our study. The most common causative agents in HAIs were Gram-negative rods (43.0\%), and the most common agent was Klebsiella spp (24.6\%)