Araştırma Çıktıları

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Author: search.filters.author.Cosar, Cemile Banu

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    The effect of hemodialysis on intraocular pressure
    (WROCLAW MEDICAL UNIV, 2018-01-01) Kilavuzoglu, Ayse Ebru Bahadir; Yurteri, Gurkan; Guven, Nurgul; Marsap, Savas; Celebi, Ali Riza Cenk; Cosar, Cemile Banu
    Background. The effect of hemodialysis (HD) on intraocular pressure (IOP) has been investigated before, but there is a lack of consensus. Clinicians dealing with renal failure patients are interested in the potential negative effects of HD on IOP and the course of glaucoma. Objectives. The aim of this study was to investigate the effects of HD on IOP in patients with end-stage renal disease. Material and methods. This prospective study included 106 patients who were receiving outpatient hemodialysis. Patient history of systemic and ophthalmologic conditions was recorded. Serum osmolality (mOsm), blood urea nitrogen (BUN), blood glucose (BG), bicarbonate (BC), and hematocrit (Hct) levels at the start of HD (pre-HD), at the end of HD (end-HD), and 30 min after HD (post-HD) were measured. Systolic and diastolic blood pressures (SBP and DBP) and IOP were measured at pre-HD, 1-hour intervals during HD, end-HD, and post-HD. Results. A significant decrease in mOsm and BUN and a significant increase in BG, BC, and Hct levels were observed at end-HD (p < 0.05). Mean IOP was 16.71 +/- 2.51 mm Hg at pre-HD, 15.52 +/- 3.18 mm Hg at end-HD, and 15.23 +/- 2.73 mm Hg at post-HD (p = 0.001
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    Correlation between corneal thickness, keratometry, age, and differential pressure difference in healthy eyes
    (NATURE RESEARCH, 2021-01-01) Colakoglu, Ahmet; Colakoglu, Iffet Emel; Cosar, Cemile Banu
    To determine the use of differential pressure difference (DPD), in air-puff differential tonometry, as a potential biomechanical measure of the cornea and elucidate its relationship with the intraocular pressure (IOP), central corneal thickness, corneal curvature, and age. This study comprised 396 eyes from 198 patients and was conducted at Acibadem University, School of Medicine, Department of Ophthalmology, Istanbul, Turkey. The central corneal curvature and refraction of the eyes were measured using an Auto Kerato-Refractometer (KR-1
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    Intrauterine Cataract Diagnosis and Follow-up
    (TURKISH OPHTHALMOLOGICAL SOC, 2020-01-01) Aksay, Sevinc; Bildirici, Ibrahim; Cosar, Cemile Banu; Alanay, Yasemin; Cigerciogullari, Engin
    In this article, we report a 21-gestational-week fetus diagnosed with congenital cataract by ultrasonography. The parents decided to terminate the pregnancy and asked for examination of the fetus. An amniocentesis was performed for fetal karyotyping. After termination of the pregnancy, fetal autopsy was conducted. Whole exome sequencing (Trio-WES) analysis of the mother and father was done from peripheral blood samples. In the pathologic autopsy report, bilateral anterior and posterior subcapsular cataracts were confirmed. Whole exome sequencing analysis revealed a previously unreported class 3 variant of uncertain significance (c755A>G {[}P.Lys252Arg]) of the CRYBB1 gene, which is associated with congenital cataract, that was homozygous in the fetus and heterozygous in the parents. The obtained result is consistent with a genetic diagnosis of isolated autosomal recessive cataract.
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    Retinal tear: an unusual complication of ocular toxoplasmosis
    (DE GRUYTER OPEN LTD, 2015-01-01) Celebi, Ali Riza Cenk; Kilavuzoglu, Ayse Ebru; Altiparmak, Ugur Emrah; Cosar, Cemile Banu; Ozkiris, Abdullah
    Purpose: It is aimed to report on a 16-year-old patient with acquired ocular toxoplasmosis complicated by a retinal tear. Methods: Retrospective medical chart review Results: A 16-year-old Caucasian female presented with vision loss in her right eye. In addition to a white active lesion between the fovea and the optic nerve head, marked vitreous opacification was noted. She was diagnosed with ocular toxoplasmosis. The patient was treated with oral azithromycin, clindamycin, and trimethoprim-sulfamethoxazole. One month later, retinochoroiditis resolved and vitreous cleared. Three months after onset, patient presented with floaters in the right eye and a retinal tear was located at the temporal region of the retina. Prophylactic argon laser treatment that encircled the retinal tear was performed. No other abnormalities were noted during 6 months of follow-up. Conclusions: Retinal tear associated with ocular toxoplasmosis is rare
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    Age-Related Changes in Corneal Epithelial Thickness Measured with an Ultrasound Pachymeter
    (DOVE MEDICAL PRESS LTD, 2022-01-01) Colakoglu, Ahmet; Cosar, Cemile Banu
    Background: There is increasing research on the aging process of the cornea and its effect on the corneal parameters measured objectively. Nevertheless, the association of corneal epithelial thickness (CET) with age has yet to be fully illustrated.Purpose: We aimed to measure CET in healthy subjects to determine its age-related variation by using an ultrasound device. Patients and Methods: A total of one hundred and three subjects were enrolled in this study and grouped according to age: Group < 30 years, 31-40 years, 41-50 years, 51-60 years, 61-70 years, and > 71 years. The CET and total central corneal thickness (CCT) of each subject were measured by the Sonogage Corneo-Gage Plus 2 (Cleveland, Ohio) ultrasound pachymeter. The relationships between thickness values, laterality, age groups, and gender were analyzed using the Jonckheere-Terpstra test. The Partial correlation test was employed to assess the effect of age on the CET and CCT. Results: The mean CET was 47.88 +/- 1.15 mu m, with no statistically significant gender-related difference between right and left eyes. In addition, the CCT difference detected between female and male eyes was insignificant. The difference in mean CET across age groups was statistically significant (p =0.029). The difference in mean CET of left eyes across age groups was statistically significant (p=0.031). The mean CET and left CET of the oldest group were significantly thinner than the younger groups.Conclusion: Ultrasound pachymeter of the corneal epithelium demonstrated that there was no correlation between age and CCT, or gender. The CET becomes thinner with age in the central zone in both genders and there is no difference between males and females. Based on these results, age has a negative effect on CET. These findings could offer further insight into age-related changes in the cornea.