Araştırma Çıktıları
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Item Suboptimal use of non-vitamin K antagonist oral anticoagulants: Results from the RAMSES study(LIPPINCOTT WILLIAMS \& WILKINS, 2016-01-01) Basaran, Ozcan; Dogan, Volkan; Beton, Osman; Tekinalp, Mehmet; Aykan, Ahmet Cagri; Kalaycioglu, Ezgi; Bolat, Ismail; Tasar, Onur; Safak, Ozgen; Kalcik, Macit; Yaman, Mehmet; Inci, Sinan; Altintas, Bernas; Kalkan, Sedat; Kirma, Cevat; Biteker, Murat; Karadeniz, Fatma Ozpamuk; Tekkesin, Ahmet Ilker; Cakilli, Yasin; Turkkan, Ceyhan; Hamidi, Mehmet; Demir, Vahit; Gursoy, Mustafa Ozan; Ozturk, Mujgan Tek; Aksan, Gokhan; Seyis, Sabri; Balli, Mehmet; Alici, Mehmet Hayri; Bozyel, Serdar; Altun, Ibrahim; Calik, Feyza; Karaca, Oguz; Helvaci, Fusun; Akay, Kadriye; Canga, Yigit; Celebi, Savas; Altuntas, Emine; Ayturk, Mehmet; Gunes, Haci Murat; Bezgin, Tahir; Aksakal, Aytekin; Cakal, Beytullah; Colak, Ayse; Kaplan, Ozgur; Tatlisu, Adem; Gozubuyuk, Gokhan; Demirelli, Selami; Kaya, Adnan; Rencuzogullari, Ibrahim; Bayram, Zubeyde; Simsek, Zeki; Civan, Murat; Batgharel, Ulaankhu; Ata, Ali Ekber; Gol, Gokhan; Mert, Gurbet Ozge; Mert, Kadir Ugur; Degirmencioglu, Aleks; Candan, Ozkan; Celebi, Ozlem Ozcan; Dogan, Cem; Yavuz, Fethi; Ulucan, Seref; Arisoy, Arif; Sahin, Bingul Dilekci; Ermis, Emrah; Gokaslan, Serkan; Pektas, Idris; Tanindi, Asli; Tekin, Kamuran; Sancar, Kadriye Memic; Cekic, Edip Guvenc; Basaran, Nesrin FilizThis study aimed to investigate the potential misuse of novel oral anticoagulants (NOACs) and the physicians' adherence to current European guideline recommendations in real-world using a large dataset from Real-life Multicenter Survey Evaluating Stroke Prevention Strategies in Turkey (RAMSES Study).RAMSES study is a prospective, multicenter, nationwide registry (ClinicalTrials.gov identifier NCT02344901). In this subgroup analysis of RAMSES study, patients who were on NOACs were classified as appropriately treated (AT), undertreated (UT), and overtreated (OT) according to the European Society of Cardiology (ESC) guidelines. The independent predictors of UT and OT were determined by multivariate logistic regression.Of the 2086 eligible patients, 1247 (59.8\%) received adequate treatment. However, off-label use was detected in 839 (40.2\%) patientsItem The Association between Subclinical Hypothyroidism and Epicardial Adipose Tissue Thickness(KOREAN SOC CARDIOLOGY, 2015-01-01) Belen, Erdal; Degirmencioglu, Aleks; Zencirci, Ertugrul; Tipi, Fatih Fahri; Altun, Ozgur; Karakus, Gultekin; Helvaci, Aysen; Zencirci, Aycan Esen; Kalaycioglu, EzgiBackground and Objectives: Subclinical hypothyroidism (SH) is considered to be a potential risk factor for cardiovascular disease. Epicardial adipose tissue (EAT) thickness is also closely related to cardiovascular disorders. The aim of this study was to evaluate whether SH is associated with higher EAT thickness. Subjects and Methods: Fifty-one consecutive patients with SH and 51 healthy control subjects were prospectively enrolled into this trial. Thyroid hormone levels, lipid parameters, body mass index, waist and neck circumference, and EAT thickness measured by echocardiography were recorded in all subjects. Results: Mean EAT thickness was increased in the SH group compared to the control group (6.7 +/- 1.4 mm vs. 4.7 +/- 1.2 mm, p<0.001). EAT thickness was shown to be correlated with thyroid stimulating hormone level (r=0.303, p=0.002). Multivariate logistic regression analysis revealed that EAT thickness was independently associated with SH \{odds ratio (OR): 3.87, 95\% confidence interval (Cl): 1.92-7.78, p<0.001Item Comparison of Pericardiocentesis in Post-Cardiac Surgery and Nonsurgical Patients with Pericardial Tamponade(SOC BRASIL CIRURGIA CARDIOVASC, 2022-01-01) Degirmencioglu, Aleks; Karakus, Gultekin; Zencirci, Ertugrul; Gullu, Ahmet Umit; Senay, SahinIntroduction:There are several approaches for pericardiocentesis. However, there is no definite suggestion about puncture location after cardiac surgery. The purpose of this study is to examine whether there is any difference regarding puncture location during pericardiocentesis in postoperative cardiac tamponade comparing to nonsurgical cardiac tamponade. Methods: We retrospectively analyzed patients who had undergone pericardiocentesis from August 2011 to December 2019. Patients were examined in two groups, nonsurgical and postsurgical, based on the etiology of pericardial tamponade. Clinical profiles, echocardiographic findings, and procedural outcomes were identified and compared. Results: Sixty-eight pericardiocenteses were performed in this period. The etiology of pericardial effusion was cardiac surgery in 27 cases and nonsurgical medical conditions in 41 cases. Baseline demographic variables were similar between the surgical and nonsurgical groups. Loculated effusion was more common in the postsurgical group (48.1\% vs. 4.9\%, P<0.001). Maximal fluid locations were different between the groups