Araştırma Çıktıları

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    Lumbar intervertebral disc herniation in childhood: a report of 7 cases
    (CUKUROVA UNIV, FAC MEDICINE, 2018-01-01) Yilmaz, Dervis Mansuri; Haciyakupoglu, Ersin; Kisi, Omer Neset; Akgul, Erol; Haciyakupoglu, Sebahattin
    Lumbar disc herniation is a rare pathology in adolescent age and these patients only constitute 1-5\% of all patients who underwent surgery for disc herniation. Trauma and family history are reported as important initiating factors for disc herniations but degenerative changes are less important than adults. The objective of this study was to treat the lumbar intervertebral disc herniation in childhood. Between 2005 and 2016, we performed interlaminarmicrodiscectomy to 7 patients younger than 15 years of age for lumbar disc herniation. These patients were evaluated for clinical features, radiological features, operative findings and outcome of surgery. All patients were complaining of low back pain, six of them had radicular pain. Although most of our patients have significant trauma histories there are no evidences of severe trauma on imaging studies. We had excellent results in all patients for the improvement of low back pain and leg pain but neurological deficits were more resistant to improvement. We had excellent results with limited laminectomy and microdiscectomy without fusion. In all cases pains improved postoperatively and they got back to their normal lifestyle in one month.
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    Analysis of Cavernous Malformations: Experience with 18 Cases
    (TURKISH NEUROSURGICAL SOC, 2019-01-01) Haciyakupoglu, Ersin; Yilmaz, Dervis Mansuri; Kinali, Burak; Akbas, Tugana; Haciyakupoglu, Sebahattin
    AIM: To analyze the results of stereotactic radiosurgery (SRS) or surgical treatment of 18 cases with cavernous malformation and report 2 cases with unusual localization and size. MATERIAL and METHODS: We present 11 and 8 patients who underwent surgery and SRS between 2010 and 2018 respectively. The operated group comprised six men and five women (mean age, 33.6 years). SRS was performed in five men and three women (mean age, 33.3 years). All patients were diagnosed and followed-up with magnetic resonance imaging. Stereotactic navigation was not used for lesion localization. The lesion, including the area with hemosiderin, was easily excised using microsurgical approach. RESULTS: Except for recurrent headache, all symptoms of patients who underwent surgery resolved rapidly. Hemorrhage developed in two of our patients after SRS. One of them refused to undergo surgery and recovered completely with steroid therapy, whereas the other underwent surgery after detection of cavernous malformation at the posterior fossa, with a dimension of 26.8x26.2 mm and occluding the fourth ventricle. CONCLUSION: In patients without significant preoperative morbidity risk, surgical excision is the gold standard of treatment. SRS is performed in surgically inaccessible, deeply located, multiple cavernous malformations in the brain stem and eloquent area. Of note, giant aneurysm is defined as an aneurysm with a diameter of at least 25 mm
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    Recurrent chronic subdural hematoma: Report of 13 cases
    (DE GRUYTER POLAND SP ZOO, 2018-01-01) Haciyakupoglu, Ersin; Yilmaz, Dervis Mansuri; Kinali, Burak; Arpaci, Taner; Akbas, Tugana; Haciyakupoglu, Sebahattin
    Chronic subdural hematoma is a frequent type of hemorrhage, which terminates with mortality if not diagnosed and treated early. The aim of this clinical study is to evaluate the patients with unilateral and bilateral recurrent chronic subdural hematoma. The study group consisted of 13 cases with unilateral and bilateral recurrent chronic subdural hematomas who underwent aggressive wide craniotomy, duraectomy, inner and outer membranectomy, dural border coagulation, incision through cortical vein trace and hang up of dural edge, between 2009 - 2016. All of our patients were diagnosed by preoperative Magnetic Resonance Imaging. We evaluated the age, gender, complaints and neurologic signs, localization and thickness of the hematoma. We can estimate that wide craniotomy, duraectomy and membranectomy is a good option in preventing recurrent chronic subdural hematoma and complications.
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    Effects of Arginine Vasopressin and V1 Receptor Antagonist on Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage: An Experimental Study
    (TURKISH NEUROSURGICAL SOC, 2018-01-01) Yilmaz, Dervis Mansuri; Haciyakupoglu, Ersin; Diril, Serkan; Sencar, Leman; Akgul, Erol; Polat, Sait; Haciyakupoglu, Sebahattin; Nazlican, Ersin
    AIM: To examine morphological, radiological and biochemical effects of arginine vasopressin ( AV) and V1 receptor antagonist on cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) in rabbits. MATERIAL and METHODS: Forty male New Zealand white rabbits were randomly divided into four groups comprising 10 rabbits each. The groups were