Araştırma Çıktıları

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Author: search.filters.author.Hakligor, Aylin

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    An important source of preanalytical error in medical laboratories: centrifugation
    (WALTER DE GRUYTER GMBH, 2021-01-01) Sonmez, Cigdem; Gumus, Alper; Senes, Mehmet; Aykal, Guzin; Taneli, Fatma; Aksungar, Fehime; Avci, Esin; Coskun, Cihan; Cinaroglu, Ipek; Colak, Ayfer; Eker, Pinar; Gucel, Funda; Hakligor, Aylin; Inal, Berrin Bercik; Orhan, Bagnu; Yilmaz, Canan
    Centrifugation separates particles within the specimen according to their shape, dimensions, and density and basically can be defined as a separation method. The centrifuge is an essential device in medical laboratories to prepare the serum, plasma, and urine samples for analysis. It is basically an electric device composed of the stationary (motor) and the motile (rotor) part. The centrifugation depends on two main variables: relative centrifugal force (RCF) and centrifugation time. The physical impact separating the specimen into its components in the centrifuge known as RCF is expressed as the multiples of gravitational acceleration (xg). RPM, defined as the number of rotations of the centrifuge perminute, shows the speed of the centrifuge. RCF value can be calculated by using RPM, and the centrifuge radius. Because models and sizes of centrifuges vary considerably, the use of gravity (g) forces instead of RPM is suggested. The centrifuges can be classified according to their usage, speed, technical specifications, and rotor type. An accurate and precise centrifugation process is essential to prevent errors in the preanalytical phase. The purpose of this document is to ensure the standardization of a good, precise protocol for the centrifugation process among the medical laboratories.
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    Transpulmonary Hypothermia with Cooled Oxygen Inhalation Shows Promising Results as a Novel Hypothermia Technique
    (GALENOS PUBL HOUSE, 2017-01-01) Acar, Yahya Ayhan; Yilmaz, Banu Karakus; Celik, Duygu Sultan; Cevik, Erdem; Topcu, Hatice; Ozsoy, Sule; Hakligor, Aylin; Cinar, Orhan
    Background: Therapeutic hypothermia was showed to improve neurologic outcome but current therapeutic hypothermia techniques have limitations. Novel techniques such as transpulmonary hypothermia with cooled oxygen inhalation may be beneficial. Aims: To evaluate the performance of transthoracic hypothermia with cooled medical oxygen inhalation as a therapeutic hypothermia method. Study Design: Animal experimentation. Methods: A total of 36 adult male Wistar-Hannover rats were used in this research. Rats were randomised into four groups: group 1, Cooled oxygen group