Araştırma Çıktıları

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Author: search.filters.author.Okur, Erdal

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    Tracheal Length in Adult Human: The Results of 100 Autopsies
    (SOC CHILENA ANATOMIA, 2016-01-01) Cinar, Ugur; Halezeroglu, Semih; Okur, Erdal; Inanici, Mehmet Akif; Kayaoglu, Semra
    The purpose of this study was to investigate the average tracheal length and number of the tracheal cartilages in Turkish people, with emphasis on the relationships to body height and sex. A hundred fresh human cadaver tracheas were harvested from 75 males and 25 females. Age, sex and body height of cadavers were recorded. All the neck and intrathoracic structures were removed. The tracheal length was measured between the subcricoid level to the carina in resting and maximally stretched positions. Average tracheal length and number of the tracheal cartilages were compared in different body height groups in both sexes. We found that average body height was 160 +/- 6.4 cm and average tracheal length in resting position was 8.5 +/- 1 cm (range 6.5-11 cm) in females and average body height was 168.6 +/- 5.6 cm, average tracheal length was 8.7 +/- 1.1 cm (range 7-11.6 cm) in males, average number of tracheal cartilages was 13.6 +/- 1.7 (range 10-16) in females and 13.3 +/- 1.6 (range 10-19) in males and average number of the tracheal cartilages per centimeter was 1.6 +/- 0.2 in female and 1.5 +/- 0.2 in male cadavers in resting position. Average tracheal length in male group was found to be significantly different in cadavers with body height equal or taller than 170 cm in comparison to cadavers with body height shorter than 170 cm (p <0.05). This study revealed that the average tracheal length in Turkish people is shorter than the reported length in literature. It is worth commenting that there is a considerable difference between the different races with regard to tracheal length. Tracheal length may vary with body height.
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    Detection of reactive oxygen metabolites in malignant and adjacent normal tissues of patients with lung cancer
    (BMC, 2013-01-01) Okur, Hacer Kuzu; Yuksel, Meral; Lacin, Tunc; Baysungur, Volkan; Okur, Erdal
    Background: Different types of reactive oxygen metabolites (ROMs) are known to be involved in carcinogenesis. Several studies have emphasized the formation of ROMs in ischemic tissues and in cases of inflammation. The increased amounts of ROMs in tumor tissues can either be because of their causative effects or because they are produced by the tumor itself. Our study aimed to investigate and compare the levels of ROMs in tumor tissue and adjacent lung parenchyma obtained from patients with lung cancer. Methods: Fifteen patients (all male, mean age 63.6 +/- 9 years) with non-small cell lung cancer were enrolled in the study. All patients were smokers. Of the patients with lung cancer, twelve had epidermoid carcinoma and three had adenocarcinoma. During anatomical resection of the lung, tumor tissue and macroscopically adjacent healthy lung parenchyma (control) that was 5 cm away from the tumor were obtained. The tissues were freshly frozen and stored at -20 degrees C. The generation of ROMs was monitored using luminol- and lucigenin-enhanced chemiluminescence (CL) techniques. Results: Both luminol (specific for. OH, H2O2, and HOCl-) and lucigenin (selective for O-2(center dot)) CL measurements were significantly higher in tumor tissues than in control tissues (P < 0.001). Luminol and lucigenin CL measurements were 1.93 +/- 0.71 and 2.5 +/- 0.84 times brighter, respectively, in tumor tissues than in the adjacent parenchyma (P = 0.07). Conclusion: In patients with lung cancer, all ROM levels were increased in tumor tissues when compared with the adjacent lung tissue. Because the increase in lucigenin concentration, which is due to tissue ischemia, is higher than the increase in luminol, which is directly related to the presence and severity of inflammation, ischemia may be more important than inflammation for tumor development in patients with lung cancer.
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    Spontaneous pneumomediastinum: report of two cases
    (TURKISH ASSOC TRAUMA EMERGENCY SURGERY, 2011-01-01) Tezel, Cagatay; Varer, Pinar; Baysungur, Volkan; Okur, Erdal; Halezeroglu, Semih
    Spontaneous pneumomediastinum (SPM) is an uncommon, benign, self-limited disorder that usually occurs in young adult males without any apparent precipitating factor or disease. SPM responds extremely well to conservative treatment without recurrence in the great majority of cases. In this report, two patients who were admitted for SPM are discussed together with the associated literature.