Araştırma Çıktıları

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    Relationship between retinal sensitivity and disease activity in patients with psoriasis vulgaris
    (HOSPITAL CLINICAS, UNIV SAO PAULO, 2015-01-01) Demir, Helin Deniz; Kalkan, Goknur; Kurt, Semiha; Gunes, Alper; Sezer, Engin; Erkorkmaz, Unal
    OBJECTIVES: Psoriasis is a hyperproliferative chronic inflammatory skin disease of unknown etiology and ocular structures and visual pathways can also be affected during the course of this disease. Subclinical optic neuritis has previously been observed in psoriatic patients in visual evoked potential studies. This trial was designed to evaluate retinal sensitivity in patients with psoriasis vulgaris. METHODS: A total of 40 eyes of 40 patients with chronic plaque-type psoriasis and 40 eyes of 40 age-and sex-matched control subjects were included in this study. The diagnosis of psoriasis was confirmed by skin biopsy. The severity was determined using the Psoriasis Area and Severity Index and the duration of the disease was recorded. After a full ophthalmological examination, including tests for color vision and pupil reactions, the visual field of each subject was assessed using both standard achromatic perimetry and short wavelength automated perimetry. RESULTS: The mean Psoriasis Area and Severity Index was 22.05 +/- 6.409. There were no significant differences in the visual field parameters of subjects versus controls using either method. There were correlations between disease severity and the mean deviations in standard achromatic perimetry and short wavelength automated perimetry and between disease severity and the corrected pattern standard deviation and pattern standard deviation of short wavelength automated perimetry (r = -0.363, r = -0.399, r = 0.515 and r = 0.369, respectively). CONCLUSIONS: Retinal sensitivity appears to be affected by the severity of psoriasis vulgaris.
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    Secretan Syndrome: A Fluctuating Case of Factitious Lymphedema
    (QUADRANT HEALTHCOM INC, 2021-01-01) Demircioglu, Deniz; Durmaz, Emel Ozturk; Sezer, Engin; Sahin, Sedef
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    Adult Type Xanthogranuloma: A Case Report
    (GALENOS YAYINCILIK, 2011-01-01) Sezer, Engin; Erkek, Emel; Sahin, Sedef; Cetin, Emel Dikicioglu
    Cutaneous xanthogranuloma is a dermatosis, clinically presenting as papules, nodules or plaques and histopathologically characterized by diffuse dermal infiltration of epithelioid cells with vesicular nuclei and conspicuous cytoplasm showing focal xanthomatous changes, and a mixed inflammation including eosinophils, neutrophils and lymphocytes. Although the disease is commonly observed in childhood, adult cases have also been reported and may cause confusion with various disorders histopathologically, including malignant melanoma. Herein, we report a case of adult type xanthogranuloma with reference to the literature.
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    A Case Report of Syringocystadenoma Papilliferum Mimicking Basal Cell Carcinoma on the Face
    (GALENOS YAYINCILIK, 2012-01-01) Sezer, Engin; Erkek, Emel; Sahin, Sedef
    Syringocystadenoma papilliferum is clinically characterized by verrucous nodules or plaques, mainly observed on the scalp during childhood. Histopathologically, epidermal invagination showing luminal epithelial cells with decapitation secretion is diagnostic. Herein, we describe an unusual late-onset case of syringocystadenoma papilliferum mimicking basal cell carcinoma on the face.