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    Defining of the Relationship Between Lung Volumes, Airway Resistance and the Apnea-Hypopnea Index
    (GALENOS PUBL HOUSE, 2018-01-01) Afsar, Gulgun Cetintas; Sarac, Sema; Babalik, Aylin; Calisir, Haluk Celalettin
    Objective: Obstructive Sleep Apnea syndrome (OSAS) is characterized by recurrent complete or partial narrowing of the upper respiratory tract during sleep and frequently a decrease in blood oxygen saturation. Upper respiratory tract gap is determined by the balance between collapsing effect of negative intraluminal pressure during inspiration and upper airway dilator muscle activity. In this study, we aimed to describe the relationship among the lung volumes and airway resistance, which are not thought to be directly taken a part in OSAS pathogenesis, and OSAS cases at different severity. Materials and Methods: Our study has been conducted on 105 cases 26 (24.8\%) of which are female and 79 (75.2\%) male who were applied polisomnography in the Ministry of Health Istanbul Sureyyapasa Chest Diseases and Chest Surgery Training and Research Hospital, Chest Disease Clinic between January 2008 and May 2008. Whole body plethysmography was performed to cases which filled patient information form containing identity informations, body mass index (BMI), neck circumference, additional disease situation, smoking anamnesis and Epworth sleepiness scale (ESS). Pulmonary function tests, lung volumes and airway resistances were recorded by looking at the expected \% values for age, color and weight. Results: Patients were divided into 4 groups according to apnea-hypopnea index
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    Obstructive Sleep Apnea and Cancer
    (GALENOS PUBL HOUSE, 2016-01-01) Demir, Ceyda Erel Kirisoglu
    Obstructive sleep apnea (OSA) is a common disorder which is associated with increased morbidity and mortality. There is growing evidence that patients with OSA have higher incidence of cancer, accelerated progression and cancer mortality. Intermittent hypoxia, oxidative stress and sleep fragmentation are hold responsible for cancer development.