Araştırma Çıktıları

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Subject: search.filters.subject.Brain tumors

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    Towards Development of a Standard Terminology of the World Health Organization Classification of Tumors of the Central Nervous System in the Turkish Language, and a Perspective on the Practical Implications of the WHO Classification for Low and Middle Income Countries
    (FEDERATION TURKISH PATHOLOGY SOC, 2022-01-01) Soylemezoglu, Figen; Oz, Buge; Egilmez, Reyhan; Pekmezci, Melike; Bozkurt, Suheyla; Danyeli, Ayca Ersen; Onguru, Onder; Kulac, Ibrahim; Tihan, Tarik
    In our manuscript, we propose a common terminology in the Turkish language for the newly adopted WHO classification of the CNS tumors, also known as the WHO CNS 5th edition. We also comment on the applicability of this new scheme in low and middle income countries, and warn about further deepening disparities between the global north and the global south. This division, augmented by the recent COVID-19 pandemic, threatens our ability to coordinate efforts worldwide and may create significant disparities in the diagnosis and treatment of cancers between the ``haves{''} and the ``have nots{''}.
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    Computerized Tomography-Guided Stereotactic Biopsy of Intracranial Lesions: Report of 500 Consecutive Cases
    (TURKISH NEUROSURGICAL SOC, 2017-01-01) Can, Songul Meltem; Turkmenoglu, Osman Nuri; Tanik, Canan; Uysal, Ender; Ozoner, Baris; Kaldirimoglu, Saime Ayca; Musluman, Ahmet Murat; Yilmaz, Adem; Cavusoglu, Halit; Bayindir, Cicek; Aydin, Yunus
    AIM: Computed tomography (CT)-guided stereotactic brain biopsy has been performed in our clinic since March 1998. In this prospective study, we examined the patient data undergoing stereotactic biopsy and the results of biopsies in 500 consecutive patients. MATERIAL and METHODS: Between the dates of March 1998 and January 2015, CT-guided stereotactic biopsies were performed by using the Leksell stereotactic frame system (Elekta Instruments EU, Sweden) in 500 patients. A total of 512 procedures were performed in patients consisting of 184 females (36.8\%) and 316 males (63.2\%), ages ranging from 3 to 81 years (mean 50.40 +/- 16.67). RESULTS: Conclusive histopathological diagnosis was not achieved in 17(3.3\%) of 512 procedures. Of the others, 173 (33.8\%) were high-grade gliomas, 103 (20.1\%) were low-grade gliomas, 36 (7\%) were malignant lymphomas, 34 (6.6\%) were other types of brain tumors, 82 (16\%) were metastasis and 67 (13.1\%) were non-tumoral lesions. Complications were occurred in ten cases: 3 tumoral bleedings, 2 hypertensive cerebral hematomas, 2 peroperative convulsions, 1 epidural hematoma, 1 myocardial infarction and 1 brain edema. The patients who developed myocardial infarction and hypertensive thalamic hematoma died. The mortality was 0.4\% and morbidity was 1.6\% in 512 procedures. CONCLUSION: CT-guided stereotactic biopsy is a reliable and a safe procedure in cases with intracranial lesions when histopathological diagnosis is required for the appropriate treatment.