Araştırma Çıktıları

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    Dental amalgam implantation and thyroid autoimmunity
    (COMENIUS UNIV, 2014-01-01) Kisahol, G.
    Objective: Mercury was heavily studied as a factor in the autoimmune processes. We aimed to observe whether mercury of amalgam is associated with Hashimoto disease. Background: 363 patients with Hashimoto's thyroiditis and 365 control subjects were included in to the study. Amalgam fillings were checked by the physician. Methods: 363 (49.9 \%) patients and 365 (50.1 \%) healthy controls were included into the study. Hashimoto's thyroiditis was diagnosed with thyroid hormones, antithyroid antibody levels, and ultrasonographic findings. Control subjects were selected from patients with no known autoimmune diseases. They were controlled with ultrasonography, as well as antibody titers. None of them had Hashimoto's thyroiditis. Results: Sex distribution of the study population was following: 319 (87.9 \%) female, 44 (12.1 \%) male in the patient group and 277 (75.9 \%) male and 88 (24.1 \%) female in healthy control subjects, respectively. Mean free T4 values for Hashimoto's thyroiditis and healthy control group were 15.30 +/- 0.76, 17.30 +/- 0.96 pmol/L and mean TSH values for Hashimoto's thyroiditis and healthy control group were 9.29 +/- 20.79, 1.20 +/- 0.32 ulU/ml. Frequency of dental amalgam implantation in patients with Hashimoto's thyroiditis was not statistically significantly different from healthy controls (p=186) (t=-1.324) Conclusions: Some studies identified mercury of amalgam as responsible for autoimmune thyroiditis. We studied whether amalgam fillings are more frequent in Hashimoto's thyroiditis patients and whether it is a causative factor for Hashimoto's thyroiditis. Statistical analysis revealed that there is no relation of amalgam with Hashimoto's thyroiditis (Tab. 1, Ref. 34). Text in PDF www.elis.sk.
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    Childhood alopecia areata: A study of 89 patients
    (DERI ZUHREVI HASTALIKLAR DERNEGI, 2014-01-01) Dogan, Sibel; Ersoy-Evans, Sibel; Gonc, Nazli; Sahin, Sedef
    Background and Design: Alopecia areata (AA) is a frequent type of acquired hair loss with a sudden onset. The aim of this study was to investigate the epidemiological and clinical features of AA and diseases associated with AA in the Turkish pediatric population. Materials and Methods: We retrospectively evaluated the medical data of patients under 16 years of age who were admitted to the pediatric dermatology outpatient clinic at Hacettepe University Hospital between 2006 and 2011 with a diagnosis of AA, alopecia totalis (AT) and alopecia universalis (AU). Results: A total of 89 patients (34 females and 55 males), were included in this study. The mean age of the subjects was 9.8 +/- 3.4 years (range:18 months-16 years). 9\% (n=8) patients had other autoimmune diseases: Hashimoto's thyroiditis in 5, vitiligo in 1, juvenile rheumatoid arthiritis (JRA) in 1 and morphea in 1 patient. AA was located on the scalp in 86.5\% (n=77) of the patients, 7.9\% (n=7) of the patients had AA on the scalp together with eyelashes, eyebrows and the body. AT was noted in 1, AU was noted in 4 patients. Severity of hair loss was <25\% in 94.3\% (n=84) of the patients according to the involved area. Hashimoto's thyroiditis was diagnosed in 5 patients