Araştırma Çıktıları

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    Do barbed sutures with different surface textures have different effects on adhesion formation and histological features? An experimental blinded study in an animal model
    (WROCLAW MEDICAL UNIV, 2019-01-01) Karacan, Tolga; Ozyurek, Eser; Turkgeldi, Lale Susan; Kiyak, Huseyin; Pesen, Simge; Yasti, Merve; Usta, Taner
    Background. The obstetrics and gynecology literature has expanded in recent years to include clinical trials assessing the use of barbed sutures. The difficulty of intracorporeal suturing continues to be a barrier to a wider use of laparoscopy. Although the use of barbed sutures has been shown to ease the process of laparoscopic suturing considerably, concerns have been raised regarding a potentially increased risk of adhesions or inflammation as a result of their use. Objectives. The aim of this study was to determine whether differences in surface textures, resulting from the variations in the geometric configurations of barbs, lead to differences in intra-abdominal adhesion formation. Material and methods. A total of 27 non-pregnant female Wistar Hannover rats, weighing 200-250 g, with intact uteri were used as an adhesion formation model. The rats were randomly assigned to 3 groups: barbed suture group 1, barbed suture group 2 and control group ( no intracorporeal suture). A 2-centimeter vertical incision was performed on the anti-mesosalpingeal side of one of the uterine horns. The incision on the uterine horn was reapproximated with a running suture, entailing 3 needle punctures and left untied at one end. Six weeks after the operation, intra-abdominal adhesion formations were investigated both clinically and histopathologically. Results. Clinical adhesion scores and histopathological parameters in both the barbed suture groups were statistically significantly higher than in the control group (p < 0.05). There was no significant difference between the barbed suture groups regarding the adhesion scores. Conclusions. The 2 types of barbed sutures with different surface textures, used for myometrial closure, form a similar profile with respect to postoperative adhesion formation.
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    A Biomechanical Comparison of Tendon Repair with a Knotless Barbed Suture and a Conventional Monofilament Suture Material: An ex-vivo Animal Experiment
    (GALENOS YAYINCILIK, 2020-01-01) Gemalmaz, Halil Can
    Objective: Our aim is to compare the ultimate tensile strength and stiffness of a 2/0 barbed suture and a 3/0 polypropylene monofilament suture in a porcine tendon repair model. Methods: Sixteen porcine Achilles tendons were transected and separated into two groups. In group I tendons were repaired with a modified knotless four-strand Kessler technique using a 2/0 V-Loc barbed suture. In group II tendons were repaired with a four-strand Kessler technique using a 3/0 monofilament conventional suture and knots were tied. All specimens were biomechanically tested for ultimate tensile strength (UTS) and stiffness. Mode of failure was also noted. Results: Five specimens in group I failed by stripping of the suture from the tendon tissue, three failed due to suture breakage. In group II two out of eight tendons failed by stripping of the suture and remaining six failed by suture breakage. Median UTS value was found to be 85.96 N (range: 63.24) in group I and 64.29 N (range: 56.84) in group II. Median stiffness value of the samples in group I was found to be 5.67 N/mm (range: 4.32) and in group II it was found to be 4.53 N/mm (range: 6.23). The statistical analysis of UTS and stiffness values revealed no significant difference between the groups (p=0.17 and p=0.56 respectively). Conclusion: A knotless Kessler tendon repair made with a 2/0 barbed suture is biomechanically equivalent to a knotted Kessler tendon repair made with a 3/0 conventional polypropylene suture in ex-vivo conditions.