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Item Eating Behaviours of Lactating Women Differ by Infant Age and Maternal BMI(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2022-01-01) Köse, Gizem; Demir, Eftal GeçgilABSTRACT Purpose: In lactation, women experience major changes in their lives as new internal and external demands for attention and care for themselves and the baby, also body mass index due to eating behaviours. Our aim was to define relationships between mindful eating and eating behaviours of breastfeeding mothers by baby’s age and maternal BMI. Methods: This cross-sectional study was conducted between October-November 2021 with 302 lactating mothers without chronic disease. Our study was approved by Ethics Committee of the Acibadem Mehmet Ali Aydinlar University. A questionnaire form that examined demographic data and Mindful Eating Questionnaire (MEQ-30) were applied. Anthropometric variables were reported by participants due to Covid-19 pandemic. Results: Mean age of our participants was 30.6±4.2 years. Mothers with obesity had lowest score in MEQ-30 (p<0.001). Lactating mothers who were underweight had highest MEQ-30 score (p<0.001). It was shown that lactating mothers have highest MEQ-30 score in the first 6 months, and MEQ-30 scores decreased as baby grows (p<0.001). Conclusion: Lactation period can be an appropriate time to bring about long-term changes in eating behavior. Healthcare professionals and teams can apply treatments focused on eating behavior and mindful eating for mothers with obesity in terms of their physical and emotional health, especially after the 6th month of breastfeeding.Item Relationship of Self-Compassion with Anxiety and Depressive Symptoms in Infertile Women(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2022-01-01) Ganime Aygün, Elif; Sancak, Barış; Ağırbaş, Ürün ÖzerABSTRACT Purpose: Infertile women have a higher rate of psychiatric symptoms compared to fertile women while depression and anxiety are among the most common psychiatric disorders in this group. Self-compassion might be a variable in predicting depression, anxiety and stress. The study aimed to evaluate self-compassion in infertile women and to examine its relationship with depression and anxiety levels. Methods: This cross-sectional study included a total number of 122 participants. The study group (n=50) consisted of women who applied to the gynaecology and obstetrics clinic for infertility treatment and were recruited consecutively. The control group (n=72) was recruited from hospital staff and their relatives, of the similar age and gender as the study group. The participants filled Self-Compassion Scale (SCS) and Hospital Anxiety and Depression Scale (HADS) in addition to sociodemographic data form. Results: SCS scores were significantly lower, and HADS scores (both depression and anxiety) were significantly higher in the study group, compared to the control group. There was a negative correlation between SCS and HADS scores (p < 0.001), indicating that lower self-compassion levels are associated with increased depression and anxiety. Duration of infertility treatment was not correlated with SCS and HADS scores (p > 0.05). Conclusion: Infertile women have higher levels of depression and anxiety while self-compassion is an influential factor in maintaining psychological well-being and preventing anxiety and depressive symptoms in this group. Self-compassion based or other interventions targeting psychological well-being of infertile women would be beneficial.Item Generic Cyclosporine in the Treatment of Dry Eye Disease(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2022-01-01) Coşar, C. Banu; Kılavuzoğlu, A. Ebru; Çelebi, A. R. Cenk; Altıparmak, U. EmrahABSTRACT Objectives: To investigate the efficacy and safety of a generic Cyclosporine 0.05% ophthalmic emulsion in chronic dry eye disease. Materails and Methods: Thirty patients with dry eye disease were included in this observational, prospective study. Patients were examined at baseline, at month -1,-3 and 6 of the study. The following were evaluated at each visit: CDVA (corrected distance visual acuity), corneal and conjunctival staining (Oxford) score, TBUT (tear break-up time), Schirmer-2 score, OSDI (Ocular Surface Disease Index) score, patient’s subjective rating scale of ocular discomfort, daily use of concomittant artificial tears, the researcher’s assessment of the global treatment response, and IOP (intraocular pressure). In addition, drug-related side effects were evaluated individually in each examination. When initiating dry eye treatment, cyclosporine was combined with topical loteprednol etabonate 0.5%. Results: There was a statistically significant improvement from baseline in corneal and conjunctival staining (decrease in mean Oxford score), TBUT, Schirmer-2 values, OSDI score, patient’s subjective rating score for ocular discomfort, and mean physician’s subjective assessment of global response to treatment at all follow-up visits (p<0.001). The mean daily use of artifical drops decreased statistically at all time points (<0.001). The most commonly reported adverse events were ocular burning (6.7%), followed by stinging (3.3%), conjunctival hyperemia (3.3%), foreign body sensation (3.3%), and visual disturbance (3.3%). Conclusion: Generic cyclosporine 0.05% ophthalmic emulsion with loteprednol etabonate 0.5% on initiation treatment has well-tolerability and improves subjective and objective measures of dry eye disease.Item Alterations of Neuroretinal and Corneal Thickness in Hashimoto’s Thyroiditis(Acıbadem Mehmet Ali Aydınlar Üniversitesi, 2022-01-01) Olcaysü, Osman Okan; Karasu, Buğra; Olcaysü, Elif; Çayır, Atilla; Çelebi, Ali Rıza CenkABSTRACT Purpose:To compare changes in macula, retinal nerve fiber layer (RNFL) and central corneal thickness (CCT) in patients with Hashimoto’s thyroiditis (HT) with age-matched healthy control group. Materials and Methods: This study was conducted with a prospective, observational, cross-sectional design. The individuals participating in the study were divided into 2 groups: patients with a diagnosis of HT (group 1, n:54 eyes) and age-matched healthy participants (group 2, n:70 eyes). Corneal, retinal and macular thickness measured by optical coherence tomography. Mean outcome measurements were CCT, intra-ocular pressure (IOP), central 1 mm foveal thickness (CFT), subfoveal choroidal thickness (SFCT), total macular volume (TMV), central 1 mm foveal volume (CFV), and RNFL thickness in superior, nasal, inferior and temporal quadrants. Results:The mean IOP was 17.07±2.34μm in group 1 and 14.20±2.76μm in group 2, respectively (p<0.001). Mean CCTs were 539.44±35.27μm and 555.06±40.53μm (p=0.001), CFTs were 227.35±17.52µm and 230.38±23.52µm (p=0.57), SFCT were 210,79±20,13µm and 268,47±24,56µm (p<0.001), TMVs were 7.16±0.35mm3 and 7.02±0.26mm3(p=0.07), CFVs were 0.17±0.01mm3 and 0.19±0.07mm3 (p=0.16) in group 1and group 2, respectively. RNFL thickness values were significantly thinner in the group 1(p<0.05) in all quadrants except for the nasal quadrant (p=0.086). Conclusion:Hypothyroidism secondary to HT may be a determining factor affecting the development of the cornea and retina. Elevated IOP and decrement of RNFL thickness in children with HT increased the risk of developing glaucoma, as well as decreased SFCT may predispose to the development of chorioretinal disorders in the futureCollection Collection