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Permanent URI for this collectionhttps://hdl.handle.net/11443/932
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Item VITAMIN D DEFICIENCY DID NOT AUGMENT THE PROGRESSION OF HIGH-FRUCTOSE-INDUCED NONALCOHOLIC FATTY LIVER DISEASE IN RATS(ISTANBUL UNIV, FAC MEDICINE, PUBL OFF, 2021-01-01) Bingul, Ilknur; Kucukgergin, Canan; Aydin, Abdurrahman Fatih; Ekici, Isin Dogan; Abbasoglu, Semra Dogru; Uysal, MujdatObjective: Vitamin D has antioxidant, anti-inflammatory and antiglycation activities, and hepatoprotective potential. There is a relationship between vitamin D deficiency (VDD) and the severity of liver disorders. VDD has been proposed to contribute to the progression of nonalcoholic fatty liver disease (NAFLD). However, experimental results are not clear. Therefore, in this study, the effects of a VDD diet on high fructose (HFr) drinking-induced NAFLD was evaluated. Material and Method: Male Wistar rats were divided into four groups as control, HFr, VDD+HFr, and VDD. Control and HFr groups were fed a control diet, and other groups with a VDD-diet for 12 weeks. HFr (30\%