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Permanent URI for this collectionhttps://hdl.handle.net/11443/932
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Item Optimal cytoreduction, depth of myometrial invasion, and age are independent prognostic factors for survival in women with uterine papillary serous and clear cell carcinomas(ELSEVIER SCIENCE BV, 2016-01-01) Solmaz, Ulas; Mat, Emre; Ekin, Atalay; Gezer, Cenk; Biler, Alper; Peker, Nuri; Ayaz, Duygu; Sanci, MuzafferObjective: The purpose of this study was to investigate the clinicopathological characteristics, treatment methods, and prognostic factors in women with uterine papillary serous carcinoma (UPSC) and uterine clear-cell carcinoma (UCCC). Study design: All patients who had undergone surgery for UPCS and UCCC between January 1995 and December 2012 were retrospectively reviewed. Patients with missing data, who did not undergo surgical staging and patients with mixed tumor histology were excluded. Multivariate regression models were used to identify the risk factors for overall survival (OS) and progression-free survival (PFS). Results: A total of 49 UPSC and 22 UCCC women were included. The majority of the patients were at stage I {[}IA, 22 (31\%) and IB, 18 (25.4\%)]. Stages II, III, and IV were identified in 9 (12.7\%), 13 (18.3\%), and 9 (12.7\%) of cases, respectively. Optimal cytoreduction was achieved in 71.8\% of cases. Recurrences occurred in 16 patients (22.5\%). The 5-year OS rates were 67\% for UPSCItem Is it safe to perform elective gynaecologic surgery during the two peaks of COVID-19 pandemic?(WILEY, 2021-01-01) Kuru, Betul; Kale, Ahmet; Basol, Gulfem; Gundogdu, Elif Cansu; Yildiz, Gazi; Mat, Emre; Usta, TanerPurpose In December 2019, the COVID-19 pandemic started in China and spread around the World. Operations were postponed in most surgical clinics to reduce the risk of contamination and increase the number of beds available in hospitals. We investigate whether elective gynaecologic surgery is safe or not under safety measures. Methods A total of 765 patients were operated on electively between 15 March and 30 October 2020 at our inpatient gynaecology clinic. We took the SARS-CoV-2 Reverse Transcriptase (RT) Polymerase Chain Reaction (PCR) test of the nasopharyngeal swab before and after the surgery. Patients were questioned for COVID-19 symptoms by phone calls on the 7th, 15th, 30th and 60th days postoperatively. Results The average age of patients was 45.6 +/- 11(19-81). Sixty-two (8.1\%) operations were performed due to gynaecologic malignancies. Three patients (0.39\%) were detected as SARS-CoV-2 RT PCR positive within 7 days after surgery. The patients did not need ICU admission or any further treatments. Conclusion Our study offers a novel perspective on elective surgery during a pandemic. The risk assessment of patients should be meticulously done and substantiated on objective variables. According to our study, in a carefully selected patient population, operating under appropriate precautions, elective gynaecologic surgical procedures during the two peaks of the COVID-19 pandemic do not pose a risk to the patients.