Araştırma Çıktıları

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Author: search.filters.author.Demir, Osman Gokhan

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    Prognostic significance of primary tumor localization in stage II and III colon cancer
    (BAISHIDENG PUBLISHING GROUP INC, 2018-01-01) Sakin, Abdullah; Arici, Serdar; Secmeler, Saban; Can, Orcun; Geredeli, Caglayan; Yasar, Nurgul; Demir, Cumhur; Demir, Osman Gokhan; Cihan, Sener
    AIM To investigate the effects of tumor localization on disease free survival (DFS) and overall survival (OS) in patients with stage I -III colon cancer. METHODS This retrospective study included 942 patients with stage. and. colon cancer, which were followed up in our clinics between 1995 and 2017. The tumors from the caecum to splenic flexure were defined as right colon cancer (RCC) and those from splenic flexure to the sigmoid colon as left colon cancer (LCC). RESULTS The median age of the patients was 58 years (range: 19-94 years). Male patients constituted 54.2\%. The rates of RCC and LCC were 48.4\% (n = 456) and 51.6\% (n = 486), respectively. During the median follow-up of 90 mo (range: 6-252 mo), 14.6\% of patients developed recurrence and 9.1\% of patients died. In patients with stage. and. disease with or without adjuvant therapy, DFS was similar in terms of primary tumor localization (stage.
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    Primary Adrenal Lymphoma with Secondary Central Nervous System Involvement: A Case Report and Review of the Literature
    (GALENOS YAYINCILIK, 2013-01-01) Aydin, Kubra; Okutur, Kerem; Bozkurt, Mustafa; Aydin, Ozlem; Namal, Esat; Ozturk, Akin; Pilanci, Kezban Nur; Kucukkaya, Reyhan Diz; Demir, Osman Gokhan
    Approximately 10\%-20\% of all systemic lymphomas have central nervous system (CNS) involvement, which has been correlated to a worsened prognosis. It is well known that secondary involvement of the adrenal glands may occur in up to 25\% of patients during the course of diffuse lymphoma. Primary adrenal lymphoma (PAL), however, is a different entity, and it is defined as the presence of adrenal lymphoma without evidence of either nodal involvement or leukemia. It has been shown that this occurrence is rarely accompanied by extranodal involvement, such as in the CNS. PAL exhibits a tendency for CNS relapse and this possibility should be examined even before symptoms are present. Herein we present a patient with PAL and secondary CNS involvement.