Araştırma Çıktıları

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    Optimal cytoreduction, depth of myometrial invasion, and age are independent prognostic factors for survival in women with uterine papillary serous and clear cell carcinomas
    (ELSEVIER SCIENCE BV, 2016-01-01) Solmaz, Ulas; Mat, Emre; Ekin, Atalay; Gezer, Cenk; Biler, Alper; Peker, Nuri; Ayaz, Duygu; Sanci, Muzaffer
    Objective: The purpose of this study was to investigate the clinicopathological characteristics, treatment methods, and prognostic factors in women with uterine papillary serous carcinoma (UPSC) and uterine clear-cell carcinoma (UCCC). Study design: All patients who had undergone surgery for UPCS and UCCC between January 1995 and December 2012 were retrospectively reviewed. Patients with missing data, who did not undergo surgical staging and patients with mixed tumor histology were excluded. Multivariate regression models were used to identify the risk factors for overall survival (OS) and progression-free survival (PFS). Results: A total of 49 UPSC and 22 UCCC women were included. The majority of the patients were at stage I {[}IA, 22 (31\%) and IB, 18 (25.4\%)]. Stages II, III, and IV were identified in 9 (12.7\%), 13 (18.3\%), and 9 (12.7\%) of cases, respectively. Optimal cytoreduction was achieved in 71.8\% of cases. Recurrences occurred in 16 patients (22.5\%). The 5-year OS rates were 67\% for UPSC